1246929-01-0 Usage
Description
Eltrombopag methyl ester, a metabolite of Eltrombopag (E508000), is a pharmaceutical compound that functions as an agonist of the Thrombopoietin (Tpo) receptor. It is characterized by its ability to stimulate the production of platelets in the body, making it a valuable asset in the treatment of thrombocytopenia.
Uses
Used in Pharmaceutical Industry:
Eltrombopag methyl ester is used as a therapeutic agent for the treatment of thrombocytopenia, a condition characterized by a low number of platelets in the blood. By acting as a Tpo receptor agonist, it promotes the proliferation and differentiation of megakaryocytes, which are the precursor cells to platelets, ultimately leading to an increase in platelet count and alleviating the symptoms of thrombocytopenia.
Additionally, eltrombopag methyl ester may also be utilized in research and development for the study of Tpo receptor agonism and its potential applications in other related conditions or diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1246929-01-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,9,2 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1246929-01:
(9*1)+(8*2)+(7*4)+(6*6)+(5*9)+(4*2)+(3*9)+(2*0)+(1*1)=170
170 % 10 = 0
So 1246929-01-0 is a valid CAS Registry Number.
1246929-01-0Relevant articles and documents
POLYMORPHS OF ELTROMBOPAG AND ELTROMBOPAG SALTS AND PROCESSES FOR PREPARATION THEREOF
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Page/Page column 16-17, (2010/10/19)
New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia.
