124857-09-6

Basic information

• Product Name: 1-(2-Acetamidophrnyl)-3-phenyl-1-propynone
• CAS NO: 124857-09-6
• Molecular Weight: 263.296
• Mol File: 124857-09-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-Acetamidophrnyl)-3-phenyl-1-propynone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Acetamidophrnyl)-3-phenyl-1-propynone(124857-09-6)
• EPA Substance Registry System: 1-(2-Acetamidophrnyl)-3-phenyl-1-propynone(124857-09-6)

Safety Data

• Hazardous Substances Data: 124857-09-6(Hazardous Substances Data)

Upstream product

• 124856-94-6 2'-Aminochalcone Dibromide 
• 108-24-7 acetic anhydride 
• 78396-00-6 2-aminochalcone 
• 131423-38-6 [E]-3-phenyl-1-(2-acetamidophenyl)prop-2-en-1-one 
• 124856-93-5 2'-Acetamidochalcone Dibromide 
• 100-52-7 benzaldehyde 
• 551-93-9 2-aminoacetophenone 
• 124856-96-8 1-(2-Acetamidophenyl)-2-bromo-3-methoxy-3-phenyl-1-propanone 

Relevant articles and documents

The Chemistry of 2'-Amino Analogues of 2'-Hydroxychalcone and Its Derivatives

The cyclization of 2'-aminochalcone (2a) and its side-chain additives has been studied for the development of syntheses of 2-aryl-4-quinolones. 2a and its 2'-acetamido 2b and 2'-benzenesulfonamido 2c derivatives underwent acid- or base-catalyzed cyclization to 1,2,3,4-tetrahydro-4-quinolones.The α,β-dibromides of 2b and 2c cyclized to cis-3-bromo-4-quinolones as did the corresponding α-bromochalcones and the α-bromo-β-methoxy additive of 2c. 2'-Acetamido-α-bromochalcone was cyclized by acid to 1,4-dihydro-2-phenyl-4-quinolone. 2'-Aminochalcone formed a stableepoxide which, with acid, gave cis-3-hydroxy-1,2,3,4-tetrahydro-3-phenyl-4-quinolone. 2'-Aminochalcones 2a-c and their additives, such as dibromide and epoxide, are useful, readily available precursors of various 2-aryl-4-quinolones.