131423-38-6

Basic information

• Product Name: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-
• CAS NO: 131423-38-6
• Molecular Formula: C17H15NO2
• Molecular Weight: 265.312
• Mol File: 131423-38-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-(131423-38-6)
• EPA Substance Registry System: Acetamide, N-[2-(1-oxo-3-phenyl-2-propenyl)phenyl]-, (E)-(131423-38-6)

Safety Data

• Hazardous Substances Data: 131423-38-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 5234-26-4 N-(2-acetylphenyl)acetamide 
• 78396-00-6 2-aminochalcone 
• 75-36-5 acetyl chloride 
• 62-53-3 aniline 
• 14371-10-9 (E)-3-phenylpropenal 
• 103-84-4 Acetanilid 
• 551-93-9 2-aminoacetophenone 
• 108-24-7 acetic anhydride 
• 19591-17-4 o-iodoacetanilide 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 577-59-3 2-acetylnitrobenzene 

Downstream Products

• 124890-66-0 1-(2-Aminophenyl)-2-bromo-3-ethoxy-3-phenyl-1-propanone 
• 124857-08-5 1-(2-Aminophenyl)-2-bromo-3-ethoxy-3-phenyl-1-propanone 
• 124857-06-3 (Z)-2'-Acetamido-α-bromochalcone 
• 124857-05-2 (E)-2'-Acetamido-α-bromochalcone 
• 124856-98-0 1-<2-(benzenesulfonamide)phenyl>-2-bromo-3-methoxy-3-phenyl-1-propanone 
• 124857-04-1 cis-1-(Phenylsulfonyl)-3-bromo-1,2,3,4-tetrahydro-2-phenyl-4-quinolone 
• 124857-07-4 cis-1-Acetyl-3-bromo-1,2,3,4-tetrahydro-2-phenyl-4-quinolone 
• 124856-97-9 1-(2-Aminophenyl)-2-bromo-3-methoxy-3-phenyl-1-propanone 
• 124856-94-6 2'-Aminochalcone Dibromide 
• 124857-09-6 1-(2-Acetamidophrnyl)-3-phenyl-1-propynone 
• 60355-89-7 4-Acetoxy-1-acetyl-1,2-dihydro-2-phenylquinoline 
• 14802-18-7 2-phenyl-1H-quinolin-4-one 
• 131423-49-9 trans-2-phenyl-3-(2'-acetaminobenzoyl)-ethylenimine 
• 136490-99-8 erythro-2-hydroxy-3-methoxy-1-(2'-acetamidophenyl)-3-phenylpropan-1-one 

Relevant articles and documents

Synthesis of [1,4]Thiazino[4,3- a]indol-10-one Derivatives through Radical Anti Aza-Michael Addition of 2′-Aminochalcones

An efficient method for the synthesis of [1,4]thiazino[4,3-a]indole derivatives using sodium chlorodifluoroacetate (ClCF2CO2Na) and elemental sulfur as the difluoromethylthiolating reagent system has been developed. Three-component reactions of 2′-aminochalcones, sulfur, and ClCF2CO2Na under basic conditions using TEMPO as the oxidant afforded [1,4]thiazino[4,3-a]indol-10-ones containing a difluoromethyl thioether moiety in good yields. Four bonds including one C-N, two C-S, and one C-C bonds are selectively formed in the sequential transformation process.

Mild palladium-catalyzed oxidative direct ortho-C-H acylation of anilides under aqueous conditions

Palladium-catalyzed cross-dehydrogenative coupling between anilides and aromatic aldehydes was achieved under aqueous conditions. A wide variety of the desired benzophenone derivatives was isolated in good to excellent yield. The reaction rate acceleration effect of acid and detergent has been demonstrated. Mechanistic insight has been obtained from quantum chemical calculations. Copyright

Palladium-catalyzed heteroannulation with acetylenic carbinols as synthons-synthesis of quinolines and 2,3-dihydro-4(1H)-quinolones

o-Iodoanilides 4 reacted with terminal acetylenic carbinols 5 under palladium-catalyzed conditions to yield o-substituted anilides 6. Most of the anilides 6 could be cyclized with NaOEt/EtOH to 2-arylquinolines 2. o-Iodoanilines 7 reacted with carbinols 5 leading to 8 which on palladium(II) assisted cyclisation afforded substituted quinolines 2. An excellent synthesis of the alkaloid dubamine (2n) is reported. Also, the anilides 6 on acid-catalyzed rearrangement, deprotection and cyclisation led to the 2-aryl-2, 3-dihydro-4(1H)-quinolones 16.