124988-56-3

Basic information

• Product Name: 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, (3S,4S)-
• CAS NO: 124988-56-3
• Molecular Formula: C34H34O7
• Molecular Weight: 554.64
• Mol File: 124988-56-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, (3S,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, (3S,4S)-(124988-56-3)
• EPA Substance Registry System: 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, (3S,4S)-(124988-56-3)

Safety Data

• Hazardous Substances Data: 124988-56-3(Hazardous Substances Data)

Usage

Furanone ring structure

The compound has a furanone ring, which is a five-membered ring with an oxygen atom and a double bond between two of the carbon atoms.

Dihydro-3-hydroxy-3,4-bis[[3-methoxy-4-(phenylmethoxy)phenyl]methyl] side chain

The compound has a side chain with two hydroxyl groups (-OH) at the 3 and 4 positions, and two methyl groups (-CH3) attached to a phenyl ring (a six-membered ring with a double bond) at the 3 and 4 positions.

(3S,4S) stereochemistry

The compound has a specific three-dimensional shape, with the 3 and 4 carbon atoms in the side chain being in the S (sinister or left) configuration.

Potential pharmaceutical applications

The compound may have biological activity due to its structure, and could be used in the development of new drugs.

Organic chemistry applications

The compound could be used in the synthesis of other compounds with similar structures or properties.

Research and development applications

The compound could be used in research and development for studying the reactivity and behaviors of furanone compounds in different environments.

Upstream product

• 1135-23-5 3-(4-hydroxy-3-methoxyphenyl)propionic acid 
• 116185-13-8 (3S,4S)-3,4-Bis-(4-benzyloxy-3-methoxy-benzyl)-dihydro-furan-2,5-dione 
• 116185-11-6 benzyl 3-[4-(benzyloxy)-3-methoxyphenyl]propanoate 
• 116185-12-7 2,3-bis<<3-methoxy-4-(phenylmethoxy)phenyl>methyl>-butanedioic acid 
• 30034-49-2 β-(4-benzyloxy-3-methoxyphenyl)propionic acid 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 111194-07-1 trans-(+/-)-dihydro-3,4-bis<<3-methoxy-4-(phenylmethoxy)phenyl>methyl>-2(3H)-furanone 
• 336101-59-8 (2R,2'S,4'S)-2-{4-[4-(benzyloxy)-3-methoxybenzyl]-2-(tert-butyl)-5-oxo-1,3-dioxolan-4-yl}-3-[4'-(benzyloxy)-3'-methoxyphenyl]propanoic acid 
• 111194-07-1 (3R,4R)-3,4-bis(4-benzyloxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 
• 336101-58-7 (R)-3-(4-Benzyloxy-3-methoxy-phenyl)-2-((2S,4S)-2-tert-butyl-5-oxo-[1,3]dioxolan-4-yl)-propionic acid 
• 336101-52-1 (2R,3S)-2-[4-(benzyloxy)-3-methoxybenzyl]-3-hydroxybutanedioic acid diisopropyl ester 
• 336101-54-3 (2R,3S)-2-(4-Benzyloxy-3-methoxy-benzyl)-3-hydroxy-succinic acid 
• 111266-03-6 (R)-(+)-3-(4-benzyloxy-3-methoxybenzyl)-γ-butyrolactone 
• 72724-00-6 1-(benzyloxy)-4-(bromomethyl)-2-methoxybenzene 

Downstream Products

• 33464-73-2 3,4-bis<(3,4-dimethoxyphenyl)methyl>dihydro-3-hydroxy-2(3H)-furanone 
• 33464-73-2 3,4-bis<(3,4-dimethoxyphenyl)methyl>dihydro-3-hydroxy-2(3H)-furanone 
• 34444-37-6 epiwikstromol 
• 34444-37-6 wikstromol 
• 34444-37-6 (-)-nortrachelogenin 
• 135043-84-4 (-)-O-dibenzylcarissanol 

Relevant articles and documents

Radical and superoxide scavenging activities of matairesinol and oxidized matairesinol

The radical and superoxide scavenging activities of oxidized matairesinols were examined. It could be assumed that the free benzylic position was important for higher radical scavenging activity. The different level of activity was observed between 7′-oxomatairesinol (Mat 2) and 7-oxomatairesinol (Mat 3). The activity of 8-hydroxymatairesinol was lower than that of matairesinol (Mat 1). The superoxide scavenging activity of the oxidized matairesinols was also demonstrated for the first time. It is assumed that the pKa value of phenol in the oxidized matairesinols affected this activity.

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Racemic and optically active α,β-dibenzyl-γ-butyrolactones (of synthetic origin) were hydroxylated in the α position with respect to the carbonyl group, using oxygen in the presence of LHDS. This led to (-)-trachelogenin 1, (-)-nortrachelogenin 2 and (+)-

Total Synthesis of (+/-)-Wikstromol

The antineoplastic prototype lignan natural product wikstromol was synthesized in racemic form by a straightforward sequence involving, as its key transformations,oxidative coupling of a carboxylic acid dianion,generation and stereoselective oxidation of a potassium enolate,and a deprotection step.The overall yield for nine steps is 29percent.Depending on the choice of oxidants for the enolate,considerable modification in the ratio of stereoisomeric products is possible.