125016-87-7Relevant articles and documents
The Mechanism of Deamination of Methoxy Substituted Tritylammonium Ions in Methanolic Aqueous Acid
Bleasdale, Christine,Golding, Bernard T.,Lee, Won Heui,Maskill, H.,Riseborough, Jane,Smits, Elly
, p. 93 - 94 (1994)
In methanolic aqueous acid, methoxy-substituted tritylammonium ions undergo heterolysis to give an equilibrium mixture of the substituted trityl cation, the corresponding alcohol (and methyl ether), and the ammonium cation via an SN1 mechanism; the detection of a reaction channel first order in hydronium ions may implicate substituted trityl cation-ammonia (ion-molecule) pairs as reactive intermediates.
Antisense modulation of G protein-coupled receptor 12 expression
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Page/Page column 19-20, (2010/11/30)
Antisense compounds, compositions and methods are provided for modulating the expression of G protein-coupled receptor 12. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding G protein-coupled receptor 12. Methods of using these compounds for modulation of G protein-coupled receptor 12 expression and for treatment of diseases associated with expression of G protein-coupled receptor 12 are provided.
Antisense modulation of phosphotyrosyl phosphatase activator expression
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Page/Page column 19, (2008/06/13)
Antisense compounds, compositions and methods are provided for modulating the expression of phosphotyrosyl phosphatase activator. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding phosphotyrosyl phosphatase activator. Methods of using these compounds for modulation of phosphotyrosyl phosphatase activator expression and for treatment of diseases associated with expression of phosphotyrosyl phosphatase activator are provided.