1253413-37-4Relevant articles and documents
A stereoselective intramolecular cyclopropanation via a de novo class of push-pull carbenes derived from DMDO-epoxidations of chiral ynamides
Li, Hongyan,Antoline, Jennifer E.,Yang, Jin-Haek,Al-Rashid, Ziyad F.,Hsung, Richard P.
, p. 1309 - 1316 (2010/09/17)
This work describes the first examples of diastereoselective intramolecular cyclopropanations of a de novo class of push-pull carbenes derived from DMDO-epoxidations of chiral ynamides. This reaction sequence essentially constitutes a tandem epoxidation-cyclopropanation that effectively gives rise to a series of structurally unique amido-cyclopropanes. A plausible mechanistic model is proposed revealing insights into this novel cyclopropanation process.