1255217-85-6Relevant articles and documents
Scalable Syntheses of Methoxyaspartate and Preparation of the Antibiotic Cystobactamid 861-2 and Highly Potent Derivatives
Moeller, Malte,Norris, Matthew D.,Planke, Therese,Cirnski, Katarina,Herrmann, Jennifer,Müller, Rolf,Kirschning, Andreas
, p. 8369 - 8372 (2019)
An improved scalable synthesis of orthogonally functionalized methoxyaspartate, the chiral hinge region element in cystobactamids, is reported. This improvement sets the stage for the total synthesis of four new cystobactamids along with cystobactamid 861