1255651-84-3

Basic information

• Product Name: dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate
• Synonyms: dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate
• CAS NO: 1255651-84-3
• Molecular Weight: 526.279
• Mol File: 1255651-84-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate(1255651-84-3)
• EPA Substance Registry System: dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate(1255651-84-3)

Safety Data

• Hazardous Substances Data: 1255651-84-3(Hazardous Substances Data)

Upstream product

• 108-46-3 recorcinol 
• 1255651-99-0 (2R,2'R)-dimethyl 2,2'-((2-iodo-1,3-phenylene)bis(oxy))dipropanoate 
• 64-19-7 acetic acid 
• 41046-67-7 2-iodoresorcinol 
• 79-21-0 peracetic acid 

Downstream Products

• 1226896-33-8 (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid 
• 1226896-38-3 (2R,2'R)-2,2'-((2-iodo-1,3-phenylene)bis(oxy))bis(N-mesitylpropanamide) 
• 1226896-63-4 (2,6-bis(((R)-1-(mesitylamino)-1-oxopropan-2-yl)oxy)-phenyl)-λ³-iodanediyl diacetate 
• 1291104-97-6 (S)-1,2-diacetoxy-1-(2,6-difluorophenyl)ethane 
• 1291105-03-7 (R)-1,2-diacetoxy-1-(2,6-difluorophenyl)ethane 
• 1291105-05-9 (R)-1-(2-chlorophenyl)ethane-1,2-diol-1,2-diacetate 
• 1291104-98-7 (S)-1-(2-chlorophenyl)ethane-1,2-diol-1,2-diacetate 
• 78692-90-7 (R)-2-methylcarbonyloxy-1-phenylethyl acetate 
• 147256-19-7 (S)-2-methylcarbonyloxy-1-phenylethyl acetate 

Relevant articles and documents

Hypervalent Iodine(III)-Catalysed Enantioselective α-Acetoxylation of Ketones

An enantioselective catalytic synthesis of α-acetoxylated ketones through I(I)/I(III) catalysis using a resorcinol/lactamide-based chiral iodoarene is reported. Catalyst turnover by in situ generation of the active iodine(III) derivative is achieved by oxidation with mCPBA in the presence of acetic acid. The prior transformation of ketones to easily accessible acetyl enol ethers is beneficial and yields up to 97 percent with enantioselectivities up to 88 percent ee are obtained using only low catalyst loadings of only 5 mol percent under mild reaction conditions.

Stereoselective Ketone Rearrangements with Hypervalent Iodine Reagents

The first stereoselective version of an iodine(III)-mediated rearrangement of arylketones in the presence of orthoesters is described. The reaction products, α-arylated esters, are very useful intermediates in the synthesis of bioactive compounds such as ibuprofen. With chiral lactic acid-based iodine(III) reagents product selectivities of up to 73 % ee have been achieved.