78692-90-7Relevant articles and documents
Structurally Defined α-Tetralol-Based Chiral Hypervalent Iodine Reagents
Hokamp, Tobias,Wirth, Thomas
, p. 8674 - 8682 (2019)
A novel class of chiral hypervalent iodine reagents containing an α-tetralol scaffold is introduced. Iodine triacetate is employed in a key step as a highly selective and efficient iodinating reagent for a short and convenient synthesis of iodine(III) derivatives. Solid-state X-ray analyses offer valuable structural information, while reactivities and stereoselectivities are investigated in three model reactions.
Alternative Strategies with Iodine: Fast Access to Previously Inaccessible Iodine(III) Compounds
Hokamp, Tobias,Mollari, Leonardo,Wilkins, Lewis C.,Melen, Rebecca L.,Wirth, Thomas
supporting information, p. 8306 - 8309 (2018/06/29)
Non-iodinated arenes can be easily and selectively converted into (diacetoxyiodo)arenes in a single step under mild conditions by using iodine triacetates as reagents. The oxidative step is decoupled from the synthesis of hypervalent iodine(III) reagents, which can now be prepared conveniently in a one-pot synthesis for subsequent reactions without prior purification. The chemistry of iodine triacetates was also expanded to heteroatom ligand exchanges to form novel inorganic hypervalent iodine compounds.
Enantioselective Vicinal Diacetoxylation of Alkenes under Chiral Iodine(III) Catalysis
W?ste, Thorsten H.,Mu?iz, Kilian
, p. 816 - 827 (2016/03/15)
A procedure for the intermolecular enantioselective dioxygenation of alkenes under iodine(III) catalysis has been developed. This protocol employs Selectfluor as the terminal oxidant together with a defined C 2-symmetric aryl iodide as the organocatalyst. This enantioselective reaction proceeds under mild conditions and converts a series of terminal and internal styrenes into the corresponding vicinal diacetoxylation products with up to 96% ee.
