125743-80-8 Usage
Description
Loratadine EP Impurity F is a fluorinated analog of Loratadine (L469575), a non-sedating antihistamine that selectively targets histamine H1-receptors. It is used as a reference compound in the pharmaceutical industry for the development, testing, and quality control of Loratadine-based medications.
Uses
Used in Pharmaceutical Industry:
Loratadine EP Impurity F is used as a reference compound for the development and quality control of Loratadine-based medications. It helps in ensuring the purity, potency, and safety of the final drug product by providing a benchmark for comparison during various stages of the drug development process.
Additionally, Loratadine EP Impurity F can be used as a research tool for studying the structure-activity relationship of Loratadine and its analogs, which may lead to the discovery of new and improved antihistamine medications with better efficacy and fewer side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 125743-80-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,7,4 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 125743-80:
(8*1)+(7*2)+(6*5)+(5*7)+(4*4)+(3*3)+(2*8)+(1*0)=128
128 % 10 = 8
So 125743-80-8 is a valid CAS Registry Number.
125743-80-8Relevant articles and documents
Antihistaminic fluoro substituted benzocycloheptapyridines
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, (2008/06/13)
Certain benzocycloheptapyridine compounds with fluorine substitution across the exocyclic double bond are prepared and they are useful as antihistaminic agents.