125769-77-9 Usage
Description
Tributyl(4,5-dihydrofuran-2-yl)tin, also known as an organotin compound or organostannane, is a chemical compound that features a tin atom bonded to three butyl groups and a 4,5-dihydrofuran-2-yl group. This organotin compound is known for its reactivity and utility in various chemical reactions, particularly in palladium-catalyzed coupling processes.
Uses
Used in Pharmaceutical Industry:
Tributyl(4,5-dihydrofuran-2-yl)tin is used as a reactant in the palladium-catalyzed Stille coupling reaction for the preparation of furan-containing aryl derivatives. This application is crucial in the synthesis of complex organic molecules and pharmaceutical compounds that may possess therapeutic properties.
Used in Chemical Synthesis:
Tributyl(4,5-dihydrofuran-2-yl)tin is utilized in the synthesis of 2,3-dihydro-5-(2-methylphenyl)furan by coupling with 2-iodotoluene in the presence of a palladium catalyst. This reaction is significant for the creation of specific organic compounds with potential applications in various fields.
Used in Advanced Organic Chemistry:
In the field of advanced organic chemistry, Tributyl(4,5-dihydrofuran-2-yl)tin is used as a reactant in the chemoselective preparation of hexatrienes. This is achieved through the tandem palladium-catalyzed Heck and Stille coupling of bromohexenyl triflates and acrylates, showcasing its versatility in complex chemical transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 125769-77-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,7,6 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 125769-77:
(8*1)+(7*2)+(6*5)+(5*7)+(4*6)+(3*9)+(2*7)+(1*7)=159
159 % 10 = 9
So 125769-77-9 is a valid CAS Registry Number.
125769-77-9Relevant articles and documents
THERAPEUTIC PYRIDAZINE COMPOUNDS AND USES THEREOF
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Page/Page column 167, (2016/09/26)
The present invention relates to compounds of formula (I): (I) and salts thereof, wherein: R1-R4 have any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of BRG1, BRM and/or PB1. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various BRG1-mediated disorders, BRM-mediated disorders and/or PB1-mediated disorders.
Adenosine receptor ligands and their use in the treatment of disease
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, (2008/06/13)
The invention relates to cyclic heteroaromatic compounds, containing at least one nitrogen atom, and to their use in the manufacture of medicaments for the treatment of diseases, related to adenosine receptor modulators, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses, hypoxia, ischaemia, seizure, substance abuse, sedation and they may be active as muscle relaxants, antipsychotics, anti epileptics, anticonvulsants and cardiaprotective agents.
UROKINASE INHIBITORS
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, (2008/06/13)
Disclosed are benzothiophene and thienothiophene derivatives useful for inhibiting urokinase activity.