927-74-2Relevant articles and documents
Vanadium-Catalyzed Oxidative Debenzylation of O-Benzyl Ethers at ppm Level
Urgoitia, Garazi,SanMartin, Raul,Herrero, María Teresa,Domínguez, Esther
, p. 3307 - 3312 (2016/10/21)
An advantageous methodology for the oxidative debenzylation of ethers has been developed. Very low amounts of a catalyst system based on vanadyl acetylacetonate and a triazole type pincer ligand allow the selective oxidative cleavage of a number of O-benzyl ethers in the presence of oxygen as the sole oxidant. The methodology tolerates a number of functional groups such as halo-, alkoxy-, or trifluoromethylarenes, alkyne, alkene, ether, and acetal units. Large-scale deprotections can be also carried out by the optimized procedure, which is amenable to enantioenriched reactants as well. (Figure presented.).
Zinc triflate: A mild and efficient catalyst for deprotection of tetrahydropyranyl ethers
Srinivasulu,Satyanarayana,Ravi Kumar
, p. 2419 - 2422 (2014/03/21)
Treatment of tetrahydropyranyl (THP) ethers with zinc triflate in methanol provides a simple and efficient process for deprotection of these ethers and the parent alcohols are obtained in excellent yields.
Chemoselective TBS deprotection of primary alcohols by means of pyridinium tribromide (Py·Br3) in MeOH
Martinez-Solorio, Dionicio,Jennings, Michael P.
, p. 5175 - 5178 (2008/12/20)
A catalytic amount of pyridinium tribromide (Py·Br3) in MeOH chemoselectively deprotects primary TBS ethers in the presence of a variety of other protecting and common functional groups in modest to excellent yields when performed at 0 °C.