125951-04-4

Basic information

• Product Name: Phosphonic acid, [(1E)-2-(4-chlorophenyl)ethenyl]-, diethyl ester
• CAS NO: 125951-04-4
• Molecular Formula: C12H16ClO3P
• Molecular Weight: 274.684
• Mol File: 125951-04-4.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [(1E)-2-(4-chlorophenyl)ethenyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(1E)-2-(4-chlorophenyl)ethenyl]-, diethyl ester(125951-04-4)
• EPA Substance Registry System: Phosphonic acid, [(1E)-2-(4-chlorophenyl)ethenyl]-, diethyl ester(125951-04-4)

Safety Data

• Hazardous Substances Data: 125951-04-4(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 87762-64-9 O,O-diethyl bismethylphosphonate 
• 3095-95-2 diethylphosphonoacetic acid 
• 1660-94-2 Tetraethyl methylenediphosphonate 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 
• 762-04-9 phosphonic acid diethyl ester 
• 1073-67-2 4-vinylbenzyl chloride 
• 101671-01-6 1-nitro-2-(4-chlorophenyl)ethylene 
• 637-87-6 1-Chloro-4-iodobenzene 
• 682-30-4 Diethyl vinylphosphonate 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 38066-16-9 diethyl [(phenylthio)methyl]phosphonate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 683-08-9 Diethyl methylphosphonate 

Downstream Products

• 85093-30-7 diethyl [2-(4-chlorophenyl)ethyl]phosphonate 

Relevant articles and documents

A stereoselective synthetic route to (E)-2-arylvinylphosphonates

Terminal alkynes 1 react with Cp2Zr(H)Cl (Cp = η5- C5H5) to give organozirconium (IV) complexes 2, which are trapped with dialkyl chlorophosphates to afford (E)-arylvinylphosphonates 3.

Convenient synthesis of α,β-unsaturated phosphonates via a Mizoroki-Heck reaction of arylboronic acids with diethyl vinylphosphonate

Palladium acetate catalyzed Mizoroki-Heck reactions of arylboronic acids with diethyl vinylphosphonates afford α,β-unsaturated phosphonates in good yields.

A facile preparation of 2-arylethenephosphonates

Vinylphosphonates 3 could be prepared with E-selectivity by the condensation of diethyl methylphosphonate 1 with a series of carbonyl compounds using diethyl chlorophosphate.

Cu(i)/Fe(III)-Catalyzed C-P cross-coupling of styrenes with H-phosphine oxides: A facile and selective synthesis of alkenylphosphine oxides and β-ketophosphonates

Cu(i)/Fe(iii)-Catalyzed phosphorylation and oxyphosphorylation of styrenes with H-phosphonates which can be controlled by varying the reaction temperature are developed. This study offers a new and expedient strategy for the synthesis of useful alkenylphosphine oxides and β-ketophosphonates in satisfactory yields. Moreover, the transformation is proposed to proceed via a radical process and exhibits a broad substrate scope and good functional group tolerance.

Stereoselective synthesis of vinylphosphonates and phosphine oxides via silver-catalyzed phosphorylation of styrenes

An efficient and stereoselective synthesis of vinylphosphonates and phosphine oxides was developed starting from styrenes using AgNO3 as the catalyst and K2S2O8 as the oxidant. The success of the reaction was fo