1260015-77-7

Basic information

• Product Name: 2-(2-iodophenoxy)-1-phenylethanol
• Synonyms: 2-(2-iodophenoxy)-1-phenylethanol
• CAS NO: 1260015-77-7
• Molecular Weight: 340.161
• Mol File: 1260015-77-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-iodophenoxy)-1-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-iodophenoxy)-1-phenylethanol(1260015-77-7)
• EPA Substance Registry System: 2-(2-iodophenoxy)-1-phenylethanol(1260015-77-7)

Safety Data

• Hazardous Substances Data: 1260015-77-7(Hazardous Substances Data)

Upstream product

• 533-58-4 2-Iodophenol 
• 70-11-1 α-bromoacetophenone 
• 20143-53-7 2-(2-iodophenoxy)-1-phenylethan-1-one 

Downstream Products

• 99783-81-0 2-phenyl-2,3-dihydrobenzo[b][1,4]dioxine 

Relevant articles and documents

Nickel-Catalyzed Asymmetric Addition of Aromatic Halides to Ketones: Highly Enantioselective Synthesis of Chiral 2,3-Dihydrobenzofurans Containing a Tertiary Alcohol

A highly enantioselective and straightforward synthetic procedure to chiral 3-hydroxy-2,3-dihydrobenzofurans has been developed by nickel/bisoxazoline-catalyzed intramolecular asymmetric addition of aryl halides to unactivated ketones, giving 2,3-dihydrobenzofurans with a chiral tertiary alcohol at the C-3 position in good yields and excellent enantioselectivities (up to 92percent yield and 98percent ee). The gram-scale reaction also proceeded smoothly without a loss of yield and enantioselectivity.