20143-53-7

Basic information

• Product Name: 2-(2-iodophenoxy)-1-phenylethan-1-one
• Synonyms: 2-(2-iodophenoxy)-1-phenylethan-1-one
• CAS NO: 20143-53-7
• Molecular Weight: 338.145
• Mol File: 20143-53-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-(2-iodophenoxy)-1-phenylethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-iodophenoxy)-1-phenylethan-1-one(20143-53-7)
• EPA Substance Registry System: 2-(2-iodophenoxy)-1-phenylethan-1-one(20143-53-7)

Safety Data

• Hazardous Substances Data: 20143-53-7(Hazardous Substances Data)

Upstream product

• 533-58-4 2-Iodophenol 
• 141-52-6 sodium ethanolate 
• 532-27-4 1-chloroacetophenone 
• 70-11-1 α-bromoacetophenone 
• 119072-55-8 tert-butylisonitrile 
• 108-95-2 phenol 
• 98-86-2 acetophenone 

Downstream Products

• 4249-72-3 2-phenoxy-1-phenylethanol 
• 127154-57-8 3-phenyl-3-hydroxy-2,3-dihydrobenzofuran 
• 98-86-2 acetophenone 
• 70-11-1 α-bromoacetophenone 
• 29909-72-6 3-Phenylbenzofuran 
• 1260015-77-7 2-(2-iodophenoxy)-1-phenylethanol 
• 19514-05-7 2-(2-chlorophenoxy)-1-phenylethan-1-one 
• 42434-88-8 2-(2-bromophenoxy)-1-phenyl-1-ethanone 
• 1258932-72-7 2-(2-iodo-5-methylphenoxy)-1-phenylethan-1-one 
• 99783-81-0 2-phenyl-2,3-dihydrobenzo[b][1,4]dioxine 
• 1620831-61-9 2-(2-iodophenoxy)-1-phenyl-4-(phenylsulfonyl)butan-1-one 
• 4202-12-4 1-phenylvinyl dimethyl phosphate 
• 1346667-95-5 1-phenyl-2-(2-(p-tolylethynyl)phenoxy)ethan-1-one 

Relevant articles and documents

Nickel-Catalyzed Intramolecular Nucleophilic Addition of Aryl Halides to Aryl Ketones for the Synthesis of Benzofuran Derivatives

A nickel-catalyzed intramolecular nucleophilic addition reaction of aryl halides to aryl ketones for the formation of benzofuran derivatives has been developed. A number of substrates bearing electron-donating or electron-withdrawing groups were subjected to the standard reaction conditions, giving the corresponding products in moderate to good yields.

Total synthesis of protosappanin A and its derivatives via palladium catalyzed ortho C-H activation/C-C cyclization under microwave irradiation

A total synthesis method for protosappanin A, which is a complex natural product with many biological activities, was developed with 6 linear steps. Dibenzo[b,d]oxepinones as the key intermediates of the synthetic route were prepared by a palladium-catalyzed ortho C-H activation/C-C cyclization under microwave irradiation. 25 derivatives of protosappanin A were obtained.

Palladium(0)-catalyzed single and double isonitrile insertion: A facile synthesis of benzofurans, indoles, and isatins

A palladium(0)-catalyzed cascade process consisting of isonitrile insertion and ?±-Csp3-H cross-coupling can be achieved for the synthesis of benzofurans and indoles. The construction of isatins by a Pd-catalyzed cascade reaction incorporating double isonitrile insertion, amination, and hydrolysis has also been achieved. The key features of this work include diverse heterocycle synthesis, phosphine-ligand-free reaction conditions, a one-pot procedure, simple and commercially available starting materials, broad functional-group compatibility, and moderate to good reaction yields.