127154-57-8

Basic information

• Product Name: 3-phenyl-3-hydroxy-2,3-dihydrobenzofuran
• Synonyms: 3-phenyl-3-hydroxy-2,3-dihydrobenzofuran
• CAS NO: 127154-57-8
• Molecular Weight: 212.248
• Mol File: 127154-57-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 3-phenyl-3-hydroxy-2,3-dihydrobenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-3-hydroxy-2,3-dihydrobenzofuran(127154-57-8)
• EPA Substance Registry System: 3-phenyl-3-hydroxy-2,3-dihydrobenzofuran(127154-57-8)

Safety Data

• Hazardous Substances Data: 127154-57-8(Hazardous Substances Data)

Upstream product

• 2553-04-0 ortho-methoxybenzophenone 
• 533-58-4 2-Iodophenol 
• 70-11-1 α-bromoacetophenone 
• 20143-53-7 2-(2-iodophenoxy)-1-phenylethan-1-one 
• 88275-87-0 3-bromo-2-methyloxybenzaldehyde 
• 1829-34-1 2-hydroxy-3-bromobenzaldehyde 
• 615-36-1 2-bromoaniline 
• 16567-18-3 8-bromoquinoline 
• 42434-88-8 2-(2-bromophenoxy)-1-phenyl-1-ethanone 
• 1018669-08-3 tert-butyl(dimethyl)[2-(1-phenylvinyl)phenoxy]silane 
• 923594-99-4 2-(2-oxo-2-phenyl-ethoxy)-phenyl boronic acid 
• 923594-93-8 2-(2-iodo-phenoxy)-1-phenyl-ethanone ethylene acetal 
• 67-56-1 methanol 

Relevant articles and documents

Photoreactivities of o-Alkoxy- and o-tert-Butylphenyl Ketones: a Dramatic Example of Conformational Inversion of Selectivity

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Redox-Neutral Coupling between Two C(sp3)?H Bonds Enabled by 1,4-Palladium Shift for the Synthesis of Fused Heterocycles

The intramolecular coupling of two C(sp3)?H bonds to forge a C(sp3)?C(sp3) bond is enabled by 1,4-Pd shift from a trisubstituted aryl bromide. Contrary to most C(sp3)?C(sp3) cross-dehydrogenative couplings, this reaction operates under redox-neutral conditions, with the C?Br bond acting as an internal oxidant. Furthermore, it allows the coupling between two moderately acidic primary or secondary C?H bonds, which are adjacent to an oxygen or nitrogen atom on one side, and benzylic or adjacent to a carbonyl group on the other side. A variety of valuable fused heterocycles were obtained from easily accessible ortho-bromophenol and aniline precursors. The second C?H bond cleavage was successfully replaced with carbonyl insertion to generate other types of C(sp3)-C(sp3) bonds.

Reductive cyclization of halo-ketones to form 3-hydroxy-2-oxindoles via palladium catalyzed hydrogenation: a hydrogen-mediated Grignard addition

Abstract The reductive cyclization of N-oxoacyl ortho-bromoanilides to form 3-hydroxy-2-oxindoles under the conditions of palladium catalyzed hydrogenation is described. This work may be viewed as a prelude to intermolecular hydrogen-mediated Grignard-typ