1265304-30-0Relevant articles and documents
Forming spirocyclohexadienone-oxocarbenium cation species in the biomimetic synthesis of amomols
Traore, Mariam,Maynadier, Marjorie,Souard, Florence,Choisnard, Luc,Vial, Henri,Wong, Yung-Sing
, p. 1409 - 1417 (2011/04/26)
The oxidation of appropriate 2-(4-hydroxyphenyl)ethyl ketones gives direct access to amomols by means of the formation of a transient spirocyclohexadienone-oxocarbenium ion that is intermolecularly intercepted by an alcohol. Furthermore, homochiral amomols and other new analogues were synthesized for the first time and were biologically evaluated on Plasmodium falciparum.(Figure Presented)