126759-61-3 Usage
General Description
1-Acetyl-6-chloro-1H-indole is a chemical compound with the molecular formula C10H8ClNO. It is also known as 6-chloroindol-3-yl acetate and is a derivative of the indole compound. This chemical is commonly used in research and pharmaceutical applications due to its potential biological activities, such as anticancer and antiviral properties. It is considered a valuable building block for the synthesis of various biologically active molecules and pharmaceutical intermediates. Additionally, 1-Acetyl-6-chloro-1H-indole has been studied for its potential use in the development of new drugs for the treatment of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 126759-61-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,7,5 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 126759-61:
(8*1)+(7*2)+(6*6)+(5*7)+(4*5)+(3*9)+(2*6)+(1*1)=153
153 % 10 = 3
So 126759-61-3 is a valid CAS Registry Number.
126759-61-3Relevant articles and documents
Intermolecular dearomative C2-arylation of N-Ac indoles activated by FeCl3
Nandi, Raj Kumar,Ratsch, Friederike,Beaud, Rodolphe,Guillot, Régis,Kouklovsky, Cyrille,Vincent, Guillaume
, p. 5328 - 5331 (2016/04/26)
We report the FeCl3-mediated direct addition of electron-rich arenes to the C2-position of electrophilic N-Ac indoles under mild conditions (room temperature, air). No functional group is required on the arene nucleophile: one of its C-H bonds is added to the C2=C3 double bond of the indole nucleus in a Friedel-Crafts-type reaction. This dearomatisation process delivered a broad range of C2-arylated indolines.
An efficient synthetic method for 2-methoxy-1,2-dihydro-3H-indol-3-ones
Kawasaki, Tomomi,Nonaka, Yoshinori,Matsumura, Ken,Monai, Miyuki,Sakamoto, Masanori
, p. 3251 - 3261 (2007/10/03)
An efficient method for synthesis of 2-methoxy-1,2-dihydro-3H-indol-3- ones using two successive oxidations of indoles is described.