127292-60-8

Basic information

• Product Name: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-
• Synonyms: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-;N,N-dimethyl-[1,1'-Biphenyl]-4-methanamine
• CAS NO: 127292-60-8
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.30218
• Mol File: 127292-60-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 112-114 °C(Press: 0.02 Torr)
• Appearance: /
• Density: 1.000±0.06 g/cm3(Predicted)
• PKA: 8.69±0.28(Predicted)
• CAS DataBase Reference: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-(127292-60-8)
• EPA Substance Registry System: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-(127292-60-8)

Safety Data

• Hazardous Substances Data: 127292-60-8(Hazardous Substances Data)

Usage

Description

[1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-, also known as 4,4'-Dimethylaminobiphenyl, is a chemical compound with the molecular formula C15H15N. It is a tertiary amine characterized by three methyl groups attached to the nitrogen atom, which provides it with unique properties and reactivity. [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethylis widely recognized for its role as a building block in the synthesis of various pharmaceuticals and organic compounds, as well as its application as a catalyst in organic reactions.

Uses

Used in Pharmaceutical Synthesis:
[1,1'-Biphenyl]-4-MethanaMine, N,N-diMethylis used as a key intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structure and reactivity make it a valuable component in the development of new medications.
Used in Organic Chemistry:
In the field of organic chemistry, [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethylis utilized as a catalyst to facilitate numerous organic reactions. Its ability to participate in various chemical processes enhances the efficiency and effectiveness of these reactions.
Used in Dye and Pigment Synthesis:
[1,1'-Biphenyl]-4-MethanaMine, N,N-diMethylis also employed as a precursor in the synthesis of dyes, pigments, and optical brighteners. Its versatile nature allows for the creation of a wide range of colorants and additives used in various industries, including textiles, plastics, and printing.
Used in Optical Brighteners:
In the production of optical brighteners, [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethylserves as an essential precursor. These brighteners are used to enhance the appearance of materials by reflecting light more effectively, making them appear brighter and more vivid. This application is particularly relevant in the textile and paper industries.

Upstream product

• 33322-67-7 N, N-dimethyl [1,1’-biphenyl]-4-carboxamide 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 15184-98-2 N,N-dimethyl-4-chlorobenzylamine 
• 98-80-6 phenylboronic acid 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 644-08-6 4-Methylbiphenyl 
• 2567-29-5 p-phenylbenzyl bromide 
• 506-59-2 N,N-dimethylammonium chloride 
• 3218-36-8 4-Phenylbenzaldehyde 
• 3597-91-9 biphenyl-4-yl methanol 
• 124-40-3 dimethyl amine 
• 6274-57-3 (4-bromobenzyl)dimethylamine 

Downstream Products

• 67362-98-5 2-([1,1′-biphenyl]-4-yl)benzo[d]thiazole 
• 5728-52-9 (4-biphenylyl)acetic acid 
• 27643-99-8 2-([1,1'-biphenyl]-4-yl)-1-phenylethan-1-ol 
• 644-08-6 4-Methylbiphenyl 
• 3218-36-8 4-Phenylbenzaldehyde 

Relevant articles and documents

Ambidextrous 'hybrid' fluorinated zwitterionic geminis: self-assembly in both organic and aqueous media

-

Controlled Reduction of Carboxamides to Alcohols or Amines by Zinc Hydrides

New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives amines. Extensive mechanistic studies by experimental and theoretical approaches imply that polymeric zinc hydride (ZnH2)∞ is responsible for alcohol formation, whereas dimeric zinc chloride hydride (H?Zn?Cl)2 is the key species for the production of amines.

METHODS FOR EXTERNAL BASE-FREE SUZUKI COUPLINGS

The present disclosure describes a method of coupling a first aromatic compound to a second aromatic compound, the method comprising: (a) preparing a reaction mixture comprising the first aromatic compound, the second aromatic compound, a catalyst and water; the reaction mixture does not contain an external base, the reaction mixture having an initial pH of from 11 to 1; the catalyst having at least one group 10 atom; the first aromatic compound having a halogen, triflate or sulfonate substituent; the second aromatic compound having a boron-containing substituent; wherein, at least one of the first aromatic compound or the second aromatic compound includes one or more heteroatom; and (b) reacting the first aromatic compound and the second aromatic compound in the reaction mixture, the reaction mixture having a final pH following reaction of the first aromatic compound and the second aromatic compound.