127621-35-6

Basic information

• Product Name: [1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenyl-
• CAS NO: 127621-35-6
• Molecular Formula: C17H13N3
• Molecular Weight: 259.31
• Mol File: 127621-35-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: [1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenyl-(127621-35-6)
• EPA Substance Registry System: [1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenyl-(127621-35-6)

Safety Data

• Hazardous Substances Data: 127621-35-6(Hazardous Substances Data)

Usage

Description

[1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenylis a heterocyclic organic compound belonging to the quinoline family. It features a molecular formula of C16H12N4 and contains a triazolo ring system. [1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenylhas been investigated for its potential pharmaceutical applications and biological activities, making it a promising candidate for the development of new drugs.

Uses

Used in Pharmaceutical Industry:
[1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenylis used as a potential drug candidate for its interesting structural features and potential biological activities. Its unique molecular composition allows for exploration in various therapeutic areas, contributing to the advancement of medicinal chemistry and drug discovery.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, [1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenylis utilized for its potential to be developed into new drugs. Its structural properties and potential interactions with biological targets make it a valuable compound for research and development, aiming to create novel therapeutic agents for various medical conditions.
Used in Drug Discovery:
[1,2,4]Triazolo[4,3-a]quinoline, 5-methyl-1-phenylis also used in drug discovery processes, where its unique characteristics and potential biological activities are assessed for the development of innovative pharmaceuticals. This involves extensive research and testing to determine its efficacy, safety, and potential applications in treating specific diseases or conditions.

Upstream product

• 21703-52-6 2-hydrazinyl-4-methylquinoline 
• 611-73-4 Benzoylformic acid 
• 100-52-7 benzaldehyde 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 90146-65-9 1-benzylidene-2-(4-methylquinolin-2-yl)hydrazine 
• 90146-65-9 benzaldehyde-(4-methyl-[2]quinolylhydrazone) 

Downstream Products

• 127621-36-7 4-chloro-5-morpholinothiocarbamoyl-1-phenyl-1,2,4-triazolo-<3,4-a>quinoline 

Relevant articles and documents

Hypervalent iodine mediated synthesis of 1-aryl/hetryl-1,2,4-triazolo[4,3-a] pyridines and 1-aryl/hetryl 5-methyl-1,2,4-triazolo[4,3-a]quinolines as antibacterial agents

Oxidation of 2-pyridyl and 2-quinylhydrazones with iodobenzene diacetate (IBD) in dichloromethane yield 1-aryl/hetryl-1,2,4-trizolo-[4,3-a] pyridines (3a-f) and 1-aryl/hetryl-5-methyl-1,2,4-triazolo[4,3-a] quinolines (6a-f). Seven compounds were tested in

KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: Efficient one-pot synthesis of 1,2,4-triazolo[4,3-a] pyridines

A one-pot approach to substituted 1,2,4-triazolo[4,3-a]pyridines has been developed that is based on a KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines. This transition-metal-free procedure was highly efficient and shows good economical and environmental advantages.

Synthesis method of 1,2,4-triazolohetercyclic compound

The invention provides a method for synthesizing a 1,2,4-triazolohetercyclic compound. The method comprises the following steps: dissolving a 2-hydrazinohetercyclic compound (I) and an aldehyde compound (II) into acetonitrile A; stirring at 25 DEG C to 80