21703-52-6

Basic information

• Product Name: (4-METHYL-QUINOLIN-2-YL)-HYDRAZINE
• Synonyms: 2-hydrazinyl-4-methylquinoline
• CAS NO: 21703-52-6
• Molecular Formula: C₁₀H₁₁N₃
• Molecular Weight: 173.22
• Mol File: 21703-52-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 147-149 °C
• Boiling Point: 377 °C at 760 mmHg
• Flash Point: 181.8 °C
• Appearance: /
• Density: 1.24g/cm³
• PKA: 5.54±0.20(Predicted)
• Water Solubility: Soluble in water.
• CAS DataBase Reference: (4-METHYL-QUINOLIN-2-YL)-HYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-METHYL-QUINOLIN-2-YL)-HYDRAZINE(21703-52-6)
• EPA Substance Registry System: (4-METHYL-QUINOLIN-2-YL)-HYDRAZINE(21703-52-6)

Safety Data

• Hazardous Substances Data: 21703-52-6(Hazardous Substances Data)

Usage

Uses

2-Hydrazino-4-methylquinoline is used as a pharmaceutical intermediate.

Upstream product

• 634-47-9 2-chloro-4-methylquinoline 
• 607-66-9 4-methylquinolin-2-ol 

Downstream Products

• 71508-44-6 1-(4-chlorobenzylidene)-2-(4-methylquinolin-2-yl)hydrazine 
• 209730-33-6 N-(4-Methyl-quinolin-2-yl)-N'-[1-(3-nitro-phenyl)-meth-(E)-ylidene]-hydrazine 
• 90146-65-9 benzaldehyde-(4-methyl-[2]quinolylhydrazone) 
• 209730-28-9 1-(4-methoxybenzylidene)-2-(4-methylquinolin-2-yl)hydrazine 
• 209730-34-7 N-(4-Methyl-quinolin-2-yl)-N'-[1-(2-nitro-phenyl)-meth-(E)-ylidene]-hydrazine 
• 90146-65-9 1-benzylidene-2-(4-methylquinolin-2-yl)hydrazine 
• 35359-25-2 5-methyl-s-triazolo<4,3-a>quinoline 
• 35359-26-3 1,5-dimethyl-[1,2,4]triazolo[4,3-a]quinoline 
• 127621-35-6 5-methyl-1-phenyl-[1,2,4]triazolo[4,3-a]quinoline 

Relevant articles and documents

Oxiranes with quinolone substitution: Stereoselective synthesis and antiviral activity

A series of new quinoline substituted oxiranes were synthesized by the reaction of 2-N-(chloroacetyl)-1-(4'-methyl-2'-quinolinyl) hydrazine and aromatic aldehydes. These compounds were tested against encephalomyocarditis virus (EMVC) and only two compounds exhibited protection against the virus.

NOVEL FUSED TRIAZOLONES AND THE USES THEREOF

This invention relates to novel compounds having the structural diagram (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.