127642-52-8

Basic information

• Product Name: ethyl (E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methyl-2-propenoate
• Synonyms: ethyl (E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methyl-2-propenoate
• CAS NO: 127642-52-8
• Molecular Weight: 214.262
• Mol File: 127642-52-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl (E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methyl-2-propenoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methyl-2-propenoate(127642-52-8)
• EPA Substance Registry System: ethyl (E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methyl-2-propenoate(127642-52-8)

Safety Data

• Hazardous Substances Data: 127642-52-8(Hazardous Substances Data)

Upstream product

• 535-11-5 Ethyl 2-bromopropionate 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 3699-66-9 ethyl 2-diethoxyphosphorylpropionate 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 21382-82-1 (carbethoxyethylidene)triphenylphosphorane 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 

Downstream Products

• 93635-76-8 (2S,3R)-3-[(4R)-2,2-dimethyl-[1,3]dioxolane-4-yl]-2,3-dihydroxy-2-methylpropionic acid ethyl ester 
• 874638-80-9 ((2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxo-tetrahydrofuran-2-yl)methyl benzoate 
• 879551-04-9 (3R,4R,5R)-3?fluoro?4?hydroxy?5?(hydroxymethyl)?3?methyltetrahydrofuran?2?one 
• 1946820-88-7 C₁₁H₂₀O₆ 
• 1033394-94-3 C₂₀H₁₇FO₆ 
• 93636-26-1 ethyl 4,5-O-isopropylidene-2-C-methyl-D-xylonate 
• 93635-77-9 C₂₇H₂₂O₈ 
• 182624-86-8 (1S,2R,3S,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexanecarbaldehyde 
• 182624-84-6 [(1S,2S,3S,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexyl]-methanol 
• 182823-32-1 [(1R,2S,3S,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexyl]-methanol 
• 182625-01-0 tert-Butyl-[(1R,2S,3R,6R)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-methoxymethoxymethyl-1-methyl-6-phenylsulfanylmethyl-cyclohexylmethoxy]-dimethyl-silane 
• 182624-82-4 2,2-Dimethyl-propionic acid (1S,2S,3S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexylmethyl ester 
• 182624-92-6 (R)-4-((1S,2S,3R,6R)-2-Benzenesulfonylmethyl-6-methoxymethoxymethyl-2,3-dimethyl-cyclohexyl)-2,2-dimethyl-[1,3]dioxolane 
• 182625-00-9 2,2-Dimethyl-propionic acid (1S,2S,3S,4R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxymethyl-4-methoxymethoxymethyl-2-methyl-cyclohexylmethyl ester 

Relevant articles and documents

Preparation method of 2-C-methyl-4, 5-O-(1-methylvinyl)-D-arabitic acid ethyl ester

The invention discloses a preparation method of 2-C-methyl-4, 5-O-(1-methylvinyl)-D-arabitic acid ethyl ester (formula I). Compared with the prior art, the preparation method has short reaction steps,reduces the use of organic solvents and generation of solid waste. At the same time, the used reagents are all conventional reagents, the method has the characteristics of simple operation, mild reaction conditions and environmental friendliness, and can achieve industrial preparation of 2-C-methyl-4, 5-O-(1-methylvinyl)-D-arabitic acid ethyl ester.

CHIRAL ROUTE TO cis-CARONALDEHYDE FROM D-MANNITOL

A chiral route to cis-caronaldehyde, a key intermediate of cis-pyrethroid insecticides as well as an efficient resolving agent for secondary alcohols, has been developed using D-mannitol as the starting material employing a sequential one-pot sodium periodate cleavage and Horner-Emmons condensation in an aqueous medium as the key stage.