127718-30-3Relevant articles and documents
Piperazine clubbed with 2-azetidinone derivatives suppresses proliferation, migration and induces apoptosis in human cervical cancer HeLa cells through oxidative stress mediated intrinsic mitochondrial pathway
Khanam, Rashmin,Kumar, Raj,Hejazi, Iram Iqbal,Shahabuddin, Syed,Meena, Ramovatar,Jayant, Vikrant,Kumar, Prabhat,Bhat, Abdul Roouf,Athar, Fareeda
, p. 113 - 131 (2018/01/27)
Abstract: Piperazine scaffolds or 2-azetidinone pharmacophores have been reported to show anti-cancer activities and apoptosis induction in different types of cancer cells. However, the mechanistic studies involve in induction of apoptosis addressing thes