127852-31-7

Basic information

• Product Name: (R)-3-(1-aminoethyl)benzonitrile
• Synonyms: Benzonitrile, 3-[(1R)-1-aminoethyl]-;(R)-3-(1-Aminoethyl)benzonitrilehydrochloride;(R)-3-(1-Aminoethyl)benzonitrile;(1R)-1-(3-Cyanophene;(R)-1-(3-Cyanophenyl)ethylamine;(R)-3-1-Aminoethy;(R)-3-(1-AMINOETHYL)BENZONITRILE-HCl;3-[(1R)-1-aMinoethyl]-
• CAS NO: 127852-31-7
• Molecular Formula: C₉H₁₀N₂
• Molecular Weight: 146.19
• Product Categories: API intermediates
• Mol File: 127852-31-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 251.4 °C at 760 mmHg
• Flash Point: 105.8 °C
• Appearance: White solid
• Density: 1.06 g/cm³
• Refractive Index: 1.557
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.59±0.10(Predicted)
• CAS DataBase Reference: (R)-3-(1-aminoethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(1-aminoethyl)benzonitrile(127852-31-7)
• EPA Substance Registry System: (R)-3-(1-aminoethyl)benzonitrile(127852-31-7)

Safety Data

• Hazardous Substances Data: 127852-31-7(Hazardous Substances Data)

Usage

General Description

(R)-3-(1-aminoethyl)benzonitrile is a chemical compound with the molecular formula C9H10N2. It is a chiral compound, meaning it has a non-superimposable mirror image. (R)-3-(1-aminoethyl)benzonitrile is used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It has a variety of potential applications, including as a precursor for the synthesis of other organic compounds and as a reagent in chemical reactions. (R)-3-(1-aminoethyl)benzonitrile is mainly used in the research and development of new drugs and other biologically active molecules. It is important for the pharmaceutical industry and academic research in organic chemistry.

InChI:InChI=1/C9H10N2/c1-7(11)9-4-2-3-8(5-9)6-10/h2-5,7H,11H2,1H3/t7-/m1/s1

Upstream product

• 1286693-23-9 3-[(1R)-1-aminoethyl]benzonitrile hydrochloride 
• 24964-64-5 3-Cyanobenzaldehyde 
• 153994-67-3 1-(R)-(+)-(3-cyanophenyl)-ethylamine 
• 258525-51-8 (S)-1-(3’-cyanophenyl)ethanol 
• 6136-68-1 3-acethylbenzonitrile 

Downstream Products

• 1539314-52-7 (R)-1-(1-(3-cyanophenyl)ethyl)-1H-indole-4,5-dicarbonitrile 
• 1539314-42-5 (R)-1-(1-(3-cyanophenyl)ethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile 
• 200402-52-4 3-(1-(R)-((3-((5-(4-azido-2-hydroxybenzoylamino)pentyl)hydroxyphosphoryl)-2-(S)-hydroxypropyl)amino)ethyl)benzoic acid 
• 200402-46-6 N-(5-((3-(1-(R)-(3-carboxyphenyl)ethylamino)-2-(S)-hydroxypropyl)hydroxyphosphoryl)pentyl)phthalimide 
• 200402-45-5 N-(5-((3-(1-(R)-(3-cyanophenyl)ethylamino)-2-(S)-hydroxypropyl)ethoxyphosphoryl)pentyl)phthalimide 

Relevant articles and documents

OXAZOLO[5,4-C]QUINOLIN-2-ONE COMPOUNDS AS BROMODOMAIN INHIBITORS

The present invention relates to compounds useful as bromodomain inhibitors. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compounds and compositions in the treatment of various diseases and disorders.

Synthesis of the nanomolar photoaffinity GABA(B) receptor ligand CGP 71872 reveals diversity in the tissue distribution of GABA(B) receptor forms

A radioiodinated probe, [125I]-CGP 71872, containing an azido group that can be photoactivated, was synthesized and used to characterize GABA(B) receptors. Photoaffinity labeling experiments using crude membranes prepared from rat brain reveale