128886-83-9

Basic information

• Product Name: 3,3-dimethyl-2-(3-fluorophenoxy)-2-(4-nitrophenyl)oxetane
• CAS NO: 128886-83-9
• Molecular Weight: 317.317
• Mol File: 128886-83-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,3-dimethyl-2-(3-fluorophenoxy)-2-(4-nitrophenyl)oxetane(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-dimethyl-2-(3-fluorophenoxy)-2-(4-nitrophenyl)oxetane(128886-83-9)
• EPA Substance Registry System: 3,3-dimethyl-2-(3-fluorophenoxy)-2-(4-nitrophenyl)oxetane(128886-83-9)

Safety Data

• Hazardous Substances Data: 128886-83-9(Hazardous Substances Data)

Upstream product

• 372-20-3 3-fluorophenol 
• 50837-40-6 α,α-Dimethyl-β-tosyloxy-p-nitropropiophenon 

Relevant articles and documents

Stabilisation of the Thromboxane Ring System by Electron-withdrawing Substituents. Mechanism and Reactivity in the Hydrolysis of Alkyl and Aryl Oxetane Acetals.

Rates of acid-catalysed hydrolysis are reported as a function of pH for eleven oxetane acetals (6) in 20percent dioxane-water.The introduction of fluorine atoms into the 2-alkoxy group results in a 103-104-fold kinetic stabilisation, and the system is also stabilised by 2-aryl substituents.The pH-rate profiles for the two most reactive compounds (3b) and (12b) show that at low pH the reaction involves rapid conversion into the intermediate hemiacetal, followed by its rate-determining decomposition.For these compounds at pH > 6, and for all other oxetane acetals studied, the ring-opening step is rate determining.No general acid catalysis is apparent.