128992-39-2

Basic information

• Product Name: N-Acetylphenylalanylphenylalanine tert-butyl ester
• CAS NO: 128992-39-2
• Molecular Weight: 410.513
• Mol File: 128992-39-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Acetylphenylalanylphenylalanine tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetylphenylalanylphenylalanine tert-butyl ester(128992-39-2)
• EPA Substance Registry System: N-Acetylphenylalanylphenylalanine tert-butyl ester(128992-39-2)

Safety Data

• Hazardous Substances Data: 128992-39-2(Hazardous Substances Data)

Upstream product

• 38879-46-8 (Z)-4-benzylidene-2-methyl-5(4H)-oxazolone 
• 16874-17-2 L-phenylalanine tert-butyl ester 
• 5469-44-3 2-methyl-4-benzyl-4H-oxazolin-5-one 

Relevant articles and documents

ASYMMETRIC SYNTHESIS OF AMINO ACIDS VIA THE CATALYTIC REDUCTION OF ACYLAMINOACRYLIC ACID AZLACTONE DERIVATIVES. 24. REDUCTIVE AMINOLYSIS OF 2-METHYL-4-BENZYLIDENE-Δ2-OXAZOLIN-5-ONE UPON TREATMENT WITH A CATALYTIC SYSTEM BASED ON S-PHENYLALANINE DERIVATIVES

Reductive aminolysis of 2-methyl-4-benzylidene-Δ2-oxazolin-5-one upon treatment with a PdCl2-S-phenylalanine ester (dimethylamide) catalytic system leads to the formation of the corresponding acylated dipeptide derivatives, with the R,S-configuration (diastereomer) predominating (DE 9-27percent).The reaction stereoselectivity in dimethoxyethane increases sharply in the presence of triethylamine additive, and in the case of S-phenylalanine methyl ester reaches 47percent.The stepwise mechanism for this process has been studied.