129332-29-2 Usage
Description
tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate is a complex organic compound with a unique molecular structure. It is characterized by the presence of a tert-butyl group, two hydroxyl groups, and a heptenoate chain. The molecule also features a 3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl moiety, which contributes to its distinct properties and potential applications.
Uses
Used in Pharmaceutical Industry:
tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate is used as a synthetic HMG-CoA reductase inhibitor for antilipemic purposes. It helps in reducing the levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood, thus playing a crucial role in the management of hyperlipidemia and cardiovascular diseases.
Used in Drug Synthesis:
Due to its unique molecular structure, tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate can be used as a key intermediate in the synthesis of various pharmaceutical compounds. Its presence of functional groups such as hydroxyl and heptenoate chain allows for further chemical modifications and the development of new drugs with improved therapeutic properties.
Used in Research and Development:
tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate can also be utilized in research and development settings to study its potential applications in various fields, such as drug discovery, medicinal chemistry, and biochemistry. Researchers can explore its interactions with biological targets, evaluate its pharmacological properties, and investigate its potential as a lead compound for the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 129332-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,3,3 and 2 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 129332-29:
(8*1)+(7*2)+(6*9)+(5*3)+(4*3)+(3*2)+(2*2)+(1*9)=122
122 % 10 = 2
So 129332-29-2 is a valid CAS Registry Number.
129332-29-2Relevant articles and documents
PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF
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, (2012/02/15)
The present invention relates to an improved process for the preparation of fluvastatin or pharmaceutical acceptable salts or derivatives thereof, in particular to a one-pot process for large scale production of Fluvastatin and salts thereof in high yield
An Improved Manufacturing Process for Fluvastatin
Fuenfschilling, Peter C.,Hoehn, Pascale,Mutz, Jean-Paul
, p. 13 - 18 (2012/12/26)
An improved manufacturing process for fluvastatin 1 has been developed by performing the condensation reaction of E-[3-(4fluorophenyl)-l-(l-methylethyl)- lH-indol-2-yl]-2-propenal, 4, with the dianion of tert-butyl acetoacetate and the subsequent low-temp
PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES BY ENZYMATIC ACYLATION
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Page 18-19, (2008/06/13)
A process for the preparation of compounds of formula (1), by enzymatic acylation to form compounds of formulae (3a) and (3a') and then reacting the compound of formula (3a) with a compound introducing the radical of formula -CH2-COOR8
