129768-24-7Relevant articles and documents
An efficient synthesis of isomeric 1-(1-Alkyl-1H-pyrazolyl) ethanones
Taydakov, Ilya,Krasnoselskiy, Sergey
, p. 1422 - 1424 (2013/02/23)
A simple and versatile general method for the preparation of N-substituted 3-, 4-, or 5-acetylpyrazoles from corresponding acids via hydrolysis and decarboxylation of substituted diethyl [(1-alkyl-1H-pyrazolyl)carbonyl]malonates was developed. Title compounds were prepared in three steps without isolation of intermediates in 48-82% overall yield.
HARMFUL ORGANISM CONTROL COMPOSITION
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Page/Page column 27, (2010/05/13)
This invention provides a harmful organism control composition having an excellent harmful organism control effect and comprising as an effective ingredient the following 4-(2-butynyloxy)-5-fluoro-6-(3,5-dimethylpiperidino)-pyrimidine (X): and a hydrazide compound represented by formula (I): wherein A1 and A2 represent, for example, an oxygen atom; R1, R2, and R3 represent, for example, a hydrogen atom, a C1-6 alkyl group optionally substituted by a halogen atom; and Q represents, for example, a methoxycarbonyl group.
Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation
Sun, Aiming,Chandrakumar, Nizal,Yoon, Jeong-Joong,Plemper, Richard K.,Snyder, James P.
, p. 5199 - 5203 (2008/02/12)
High-throughput screening has identified 1-methyl-3-(trifluoromethyl)-N-[4-(pyrrolidinylsulfonyl)phenyl]-1H-pyrazole-5-carboxamide 16677 as a novel and potent (IC50 = 35-145 nM) inhibitor against multiple primary isolates of diverse measles vir