130000-78-1

Basic information

• Product Name: (4-methoxy-3,5-dimethylpyridin-2-yl)methanamine
• Synonyms: (4-methoxy-3,5-dimethylpyridin-2-yl)methanamine;1-(4-methoxy-3,5-dimethyl-2-pyridinyl)methanamine(SALTDATA: 2HCl);4-methoxy-3,5-dimethyl-2-Pyridinemethanamine;1-(4-methoxy-3,5-dimethyl-2-pyridinyl)methanamine
• CAS NO: 130000-78-1
• Molecular Formula: C₉H₁₄N₂O
• Molecular Weight: 166.22026
• Mol File: 130000-78-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 274.59 °C at 760 mmHg
• Flash Point: 119.868 °C
• Appearance: /
• Density: 1.044 g/cm³
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: (4-methoxy-3,5-dimethylpyridin-2-yl)methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxy-3,5-dimethylpyridin-2-yl)methanamine(130000-78-1)
• EPA Substance Registry System: (4-methoxy-3,5-dimethylpyridin-2-yl)methanamine(130000-78-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 130000-78-1(Hazardous Substances Data)

Usage

General Description

(4-Methoxy-3,5-dimethylpyridin-2-yl)methanamine, also known as Mirodenafil, is a chemical compound with potential pharmaceutical applications. It belongs to the class of pyridine derivatives and is structurally related to sildenafil, a well-known erectile dysfunction drug. Mirodenafil has been studied for its potential use as a treatment for erectile dysfunction and other sexual performance issues. It is believed to work by inhibiting the enzyme phosphodiesterase type 5 (PDE-5), which increases blood flow to the penis and helps to achieve and maintain an erection. Additionally, Mirodenafil has shown potential for use as a vasodilator and may have applications in treating other cardiovascular conditions. Further research and clinical trials are needed to determine its safety and efficacy for these uses.

InChI:InChI=1/C9H14N2O/c1-6-5-11-8(4-10)7(2)9(6)12-3/h5H,4,10H2,1-3H3

Upstream product

• 946071-49-4 2-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)isoindoline-1,3-dione 
• 104916-41-8 3,5-dimethyl-4-methoxy-2-cyanopyridine 
• 86604-75-3 2-(chloromethyl)-4-methoxy-3,5-dimethylpyridine hydrochloride 

Downstream Products

• 6626-74-0 N,N'-bis(2-ethylhexyl)pyromellitic diimide 
• 1039745-25-9 C₂₇H₃₁N₃O₅ 
• 1044243-97-1 2-amino-4-chloro-8-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7,8-dihydropteridin-6(5H)-one 
• 86604-78-6 (4-methoxy-3,5-dimethylpyridin-2-yl)methanol 

Relevant articles and documents

BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES

The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.

Origins of selectivity in a colorimetric charge-transfer sensor for diols

(Chemical Equation Presented) Bispyridyl hydrogen bonding receptor 1 forms colored charge transfer (CT) complexes with complementary phenols and naphthols. Despite its low association constants of ～101 M-1, receptor 1 was highly selective forming CT complexes of varying color and intensity with different diol guests. The selectivity of 1 was correlated with the ability of its CT band to simultaneously yield information about the association constant and the electronic structure of the phenols and naphthols.

3,5-dimethyl-4-methoxypyridine derivatives

A process for the preparation of compounds of formula I STR1 in which X is the radical OH or Cl, by the catalytic hydrogenation of 3,5-dimethyl-4-methoxy-2-cyanopyridine, subsequent reaction of the resulting 3,5-dimethyl-4-methoxy-2-aminomethylpyridine to give 3,5-dimethyl-4-methoxy-2-hydroxymethylpyridine and, if desired, chlorination to give 3,5-dimethyl-4-methoxy-2-chloromethylpyridine, and the novel intermediate 3,5-dimethyl-4-methoxy-2-aminomethylpyridine.