130532-95-5

Basic information

• Product Name: α-(4-pyrimidyl)phenylacetonitrile
• Synonyms: α-(4-pyrimidyl)phenylacetonitrile
• CAS NO: 130532-95-5
• Molecular Weight: 195.224
• Mol File: 130532-95-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α-(4-pyrimidyl)phenylacetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: α-(4-pyrimidyl)phenylacetonitrile(130532-95-5)
• EPA Substance Registry System: α-(4-pyrimidyl)phenylacetonitrile(130532-95-5)

Safety Data

• Hazardous Substances Data: 130532-95-5(Hazardous Substances Data)

Upstream product

• 289-95-2 PYRIMIDINE 
• 140-29-4 phenylacetonitrile 
• 134340-12-8 α(6-chloro-4-pyrimidyl)phenylacetonitril 
• 6104-41-2 4-methoxypyrimidine 

Downstream Products

• 68027-80-5 phenyl(4-pyrimidinyl)methanone 
• 64660-82-8 4-benzylpyrimidine 

Relevant articles and documents

Preparation of Heteroaryl Phenylmethanes and a 13C and 15N NMR Spectroscopic Study of their Conjugate Carbanions. Rotational Isomerism and Charge Maps of the Anions and Ranking of the Charge Demands of the Heterocycles

2-Benzylpyridazine, 4-benzylpyrimidine, 2-benzylpyrimidine and 2-benzylpyrazine, (5-8) have been prepared in order to study their 13C and 15N spectra and those of their conjugate carbanions (1-4).These systems are aza-homologues of the previously reported

REACTION OF METHOXY-N-HETEROAROMATICS WITH PHENYLACETONITRILE UNDER BASIC CONDITIONS

The monomethoxyl derivatives of various ?-electron deficient N-heteroaromatics reacted with phenylacetonitrile in tetrahydrofuran in the presence of sodium hydride to give α-phenyl-N-heteroareneacetonitriles in the yields ranging from 45 to 78percent.On the contrary, the reaction of these methoxyl derivatives with ethyl cyanoacetate or malononitrile under similar conditions was restricted within narrow limits.The synthesis of benzoyl-N-heteroaromatics by the air-oxidation of α-phenyl-N-hetroareneacetonitriles was described additionally.