13186-21-5 Usage
Description
N-Norsinoactine is an alkaloid isolated from Croton balsamifera Jacq. and C. javens. It crystallizes from AcOEt with one mole of solvent that is difficult to remove. N-Norsinoactine exhibits specific optical rotation ([α]D-107°) in ethanol and characteristic absorption maxima in its ultraviolet spectrum at 241 (shoulder) and 275 nm. The base reacts with FeCl3 to produce a deep blue color. Its structure has been elucidated through chemical degradation, NMR, and mass spectrometry analysis.
Uses
N-Norsinoactine is used as a bioactive compound in pharmaceutical research for its potential therapeutic properties. Its unique structure and reactivity with FeCl3 suggest that it may have applications in the development of new drugs and treatments. However, further research is needed to fully understand its potential uses and benefits in various industries.
References
Chambers, Haynes, Stuart., Chem. Commun., 449 (1966)Stuart, Chambers., Tetrahedron Lett., 2879 (1967)
Check Digit Verification of cas no
The CAS Registry Mumber 13186-21-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,8 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13186-21:
(7*1)+(6*3)+(5*1)+(4*8)+(3*6)+(2*2)+(1*1)=85
85 % 10 = 5
So 13186-21-5 is a valid CAS Registry Number.
13186-21-5Relevant articles and documents
Pharmacodynamic investigation of (±)-salutaridine
Kardos,Blasko,Simonyi,Szantay Cs.
, p. 1758 - 1759 (2007/10/02)
The alkaloid 5,6,8,14-tetradehydro-4-hydroxy-3,6-dimethoxy-17-methyl-morphinan-7-one(± )-salutaridine) was found to possess 3H-γ-aminobutryic acid (3H-GABA) displacing activity (IC50 3H-diazepam binding by increasing concentration of (±)-salutaridine follows a maximum curve, indicating (±)-salutaridine to be a partial agonist in the GABA/benzodiazepine receptor complex.
