132015-40-8

Basic information

• Product Name: 3-phenyl-pentanedioic acid monomethyl ester
• Synonyms: 3-phenyl-pentanedioic acid monomethyl ester
• CAS NO: 132015-40-8
• Molecular Weight: 222.241
• Mol File: 132015-40-8.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: 3-phenyl-pentanedioic acid monomethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-pentanedioic acid monomethyl ester(132015-40-8)
• EPA Substance Registry System: 3-phenyl-pentanedioic acid monomethyl ester(132015-40-8)

Safety Data

• Hazardous Substances Data: 132015-40-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 4160-80-9 3-phenylglutaric acid anhydride 
• 100-52-7 benzaldehyde 
• 936735-54-5 C₁₉H₂₀O₄ 
• 19006-47-4 dimethyl 3-phenylpentanedioate 
• 4165-96-2 3-phenylglutaric acid 
• 116-11-0 2-Methoxypropene 
• 145207-45-0 (R)-3-(4-Methoxy-phenyl)-4,6-dioxo-2-phenyl-5-[1-phenyl-meth-(Z)-ylidene]-[1,3]oxazinane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 74-88-4 methyl iodide 

Downstream Products

• 131906-21-3 p-nitrophenyl 5-oxo-3-phenylpentanoate 
• 131906-19-9 4-(1,3-dioxolan-2-yl)-3-phenylbutanoic acid 
• 131906-18-8 methyl 4-(2,5-dioxolanyl)-3-phenylbutanoate 
• 131906-20-2 5-oxo-3-phenylpentanoic acid 
• 132015-42-0 methyl 5-oxo-3-phenylpentanoate 
• 71302-21-1 (4R)-4-phenyltetrahydro-2H-pyran-2-one 
• 145207-48-3 (S)-3-Phenyl-pentanedioic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester methyl ester 
• 19006-47-4 dimethyl 3-phenylpentanedioate 
• 61198-49-0 (S)-4-phenyltetrahydro-2H-pyran-2-one 
• 131906-11-1 p-nitrophenyl 4-carbomethoxy-3-phenylbutanoate 

Relevant articles and documents

Enantioselective acyl-transfer catalysis by fluoride ions

The asymmetric nucleophilic catalysis by fluoride ions at a carbon-based electrophile has been demonstrated for the first time. Using a library of ad hoc designed bifunctional phase-transfer catalysts in which both the anion and the cation are directly involved in the reaction, the desymmetrisation of meso-succinic and -glutaric anhydrides is possible.19F NMR spectroscopic studies support the intermediacy of an acyl fluoride intermediate.

Organocatalytic kinetic resolution of racemic secondary nitroallylic alcohols combined with simultaneous desymmetrization of prochiral cyclic anhydrides

This study describes an organocatalytic kinetic resolution of racemic secondary nitroallylic alcohols (2) combined with simultaneous desymmetrization of prochiral cyclic anhydrides (1). The experimental results revealed that enantioselective alcoholysis of 3-substituted glutaric anhydrides afforded hemiesters (3) with high levels of enantioselectivities (up to 99% ee) in the presence of cinchonidine-derived thiourea catalyst (IV). The highly optical enrichment (up to 95% ee) of (S)-nitroallylic alcohols (2) was recovered.

Increased selectivity of novozym 435 in the asymmetric hydrolysis of a substrate with high hydrophobicity through the use of deep eutectic solvents and high substrate concentrations

The effects of the reaction medium and substrate concentration were studied on the selectivity of Novozym 435 using the asymmetric hydrolysis of dimethyl-3-phenylglutarate as a model reaction. Results show that the use of choline chloride ChCl:urea/phosph

Novel amide-functionalized chloramphenicol base bifunctional organocatalysts for enantioselective alcoholysis of meso-cyclic anhydrides

A family of novel chloramphenicol base-amide organocatalysts possessing a NH functionality at C-1 position as monodentate hydrogen bond donor were developed and evaluated for enantioselective organocatalytic alcoholysis of meso-cyclic anhydrides. These structural diversified organocatalysts were found to induce high enantioselectivity in alcoholysis of anhydrides and was successfully applied to the asymmetric synthesis of (S)-GABOB.