13208-19-0

Basic information

• Product Name: 1,3-Bis(2-chlorophenyl)urea
• Synonyms: 1,3-Bis(2-chlorophenyl)urea;N,N'-Bis(2-chlorophenyl)urea
• CAS NO: 13208-19-0
• Molecular Formula: C₁₃H₁₀Cl₂N₂O
• Molecular Weight: 281.1373
• Mol File: 13208-19-0.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 310.8°Cat760mmHg
• Flash Point: 141.8°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 0.000587mmHg at 25°C
• Refractive Index: 1.699
• CAS DataBase Reference: 1,3-Bis(2-chlorophenyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Bis(2-chlorophenyl)urea(13208-19-0)
• EPA Substance Registry System: 1,3-Bis(2-chlorophenyl)urea(13208-19-0)

Safety Data

• Hazardous Substances Data: 13208-19-0(Hazardous Substances Data)

Usage

Type of compound

Man-made chemical compound

Primary use

Herbicide

Mechanism of action

Non-selective inhibitor of photosynthesis in plants

How it works

Disrupts the electron transport chain in chloroplasts

Effects on plants

Inhibition of growth and eventual death

Application areas

Agricultural crops, non-agricultural land, and industrial settings

Purpose

Control of unwanted vegetation

Environmental concern

Persistence in soil and water

Toxicity

Toxic to aquatic organisms

Health risk

Classified as a possible human carcinogen

Potential health risks

Concerns for people who come into contact with the chemical

InChI:InChI=1/C13H10Cl2N2O/c14-9-5-1-3-7-11(9)16-13(18)17-12-8-4-2-6-10(12)15/h1-8H,(H2,16,17,18)

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 88-73-3 2-Chloronitrobenzene 
• 124-38-9 carbon dioxide 
• 139931-65-0 C₉H₁₄ClNSi 
• 95-51-2 o-chloroaniline 
• 503-38-8 trichloromethyl chloroformate 
• 141-97-9 ethyl acetoacetate 
• 694-80-4 2-bromo-1-chlorobenzene 
• 57-13-6 urea 
• 42792-92-7 3-(2-chloro-anilino)-trans-crotonic acid ethyl ester 
• 105-45-3 acetoacetic acid methyl ester 
• 1219-68-7 1,3-bis(2-chlorophenyl)thiourea 
• 78695-60-0 phenyl N-phenylphosphoramidoazidate 

Downstream Products

• 96461-96-0 N,N'-bis-(2-chloro-4-nitro-phenyl)-urea 
• 50906-31-5 N-(2-chlorophenyl)-N’-(4-methoxyphenyl)urea 
• 53117-16-1 ethyl N-(2-chlorophenyl)oxamate 
• 5255-70-9 ethyl N-(o-chlorophenyl) carbamate 

Relevant articles and documents

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Method for preparing symmetric urea compound

The invention provides a novel reaction system for synthesizing a symmetric urea compound by taking CO2 as a carbonylation reagent, wherein Lewis base and hydrosilane are used as accelerators and efficiently enable an aromatic/aliphatic primary amine compound to react with normal-pressure CO2 to generate corresponding symmetric urea compounds containing different functional groups under mild conditions (100 DEG C, diglyme). According to the method, normal-pressure CO2 is used as an environmentally-friendly non-toxic carbonylation reagent, and cheap Lewis base and PMHS (industrial silicon waste) are used as accelerators, so that the use of toxic carbonylation reagents, isocyanate, high-pressure CO2, expensive dehydrating agents and precious metals is avoided, purification and separation ofintermediates are not needed, pure products can be obtained only through simple suction filtration and separation after the reaction is finished, and the method is an efficient and novel synthesis method and has high industrial application value.

N,N'-disubstituted urea compound and synthesis method thereof

The invention discloses an N,N'-disubstituted urea compound and a preparation method thereof. N-alkyl acyloxy amide is taken as a raw material and a dichloro(p-cymene)ruthenium(II) dimer complex is taken as a catalyst for carrying out a reaction in an organic solvent under the presence of silver acetate, and the N,N'-disubstituted urea compound is prepared. Compared with the prior art, the methodhas the following advantages that only an amide derivative is taken as a raw material, reaction conditions are mild, the application range of substrates is wide, operation is simple and convenient, the catalyst is low in price, and selectivity of the product is high.