5255-70-9Relevant articles and documents
Nickel(II)- And Silver(I)-Catalyzed C-H Bond Halogenation of Anilides and Carbamates
Kianmehr, Ebrahim,Afaridoun, Hadi
, p. 1513 - 1523 (2020/12/14)
ortho -C-H bond halogenation of anilides and N -aryl carbamates using easily available N -halosuccinimides (NXS) as the active halogenation reagent in the presence of nickel or silver catalyst has been developed. This method provides a new approach to 2-haloanilides and carbamates, which may serve as starting materials for the synthesis of pharmaceutically and biologically active compounds.
Structure-activity relationship study of arylsulfonylimidazolidinones as anticancer agents
Sharma, Vinay K.,Lee, Ki-Cheul,Venkateswararao, Eeda,Joo, Cheonik,Kim, Min-Seok,Sharma, Niti,Jung, Sang-Hun
supporting information; experimental part, p. 6829 - 6832 (2011/12/22)
In an effort to find novel N-arylsulfonylimidazolidinones as highly potent anticancer agent, the structure-activity relationship of ethyl 2-methyl-4-(2-oxo-4-phenylimidazolidin-1-ylsulfonyl)phenylcarbamate was explored through synthesis and evaluation of
Facile double-lithiation of a transient urea: Vicarious ortho -metalation of aniline derivatives
Houlden, Chris E.,Lloyd-Jones, Guy C.,Booker-Milburn, Kevin I.
supporting information; experimental part, p. 3090 - 3092 (2010/09/05)
A convenient one-pot method for the conversion of phenylisocyanate into ortho-functionalized aniline derivatives has been developed. The reaction proceeds via the selective ortho-metalation of a transient labile urea, which can be considered as a synthetic equivalent of 2-lithio-phenylisocyanate, a highly improbable intermediate.