1325713-83-4

Basic information

• Product Name: (Z)-ethyl 3-(allylamino)-3-(4-(trifluoromethyl)phenyl)acrylate
• Synonyms: (Z)-ethyl 3-(allylamino)-3-(4-(trifluoromethyl)phenyl)acrylate
• CAS NO: 1325713-83-4
• Molecular Weight: 299.293
• Mol File: 1325713-83-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-ethyl 3-(allylamino)-3-(4-(trifluoromethyl)phenyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-ethyl 3-(allylamino)-3-(4-(trifluoromethyl)phenyl)acrylate(1325713-83-4)
• EPA Substance Registry System: (Z)-ethyl 3-(allylamino)-3-(4-(trifluoromethyl)phenyl)acrylate(1325713-83-4)

Safety Data

• Hazardous Substances Data: 1325713-83-4(Hazardous Substances Data)

Upstream product

• 106263-53-0 ethyl 3-oxo-3-(4-(trifluoromethyl)phenyl)propanoate 
• 107-11-9 1-amino-2-propene 

Downstream Products

• 1325714-24-6 ethyl 4-formyl-2-(4-(trifluoromethyl)phenyl)-1H-pyrrole-3-carboxylate 

Relevant articles and documents

Copper-mediated oxidative transformation of N-allyl enamine carboxylates toward synthesis of azaheterocycles

A method for synthesis of 3-azabicyclo[3.1.0]hex-2-enes has been developed by intramolecular cyclopropanation of readily available N-allyl enamine carboxylates. Two complementary reaction conditions, CuBr-mediated aerobic and CuBr2-catalyzed-PhIO2-mediated systems effectively induced stepwise cyclopropanation via carbocupration of alkenes. Oxidative cyclopropane ring-opening of 5-substituted 3-azabicyclo[3.1.0]hex-2-enes was also developed for synthesis of highly substituted pyridines. In addition, diastereoselective reduction of 3-azabicyclo[3.1.0]hex-2-enes to 3-azabicyclo[3.1.0]hexanes was achieved using NaBH3CN in the presence of acetic acid.