133095-94-0

Basic information

• Product Name: (S)-4-Hydroxy-4-(3-iodo-5-methoxy-4-propoxy-phenyl)-butyric acid
• Synonyms: (S)-4-Hydroxy-4-(3-iodo-5-methoxy-4-propoxy-phenyl)-butyric acid
• CAS NO: 133095-94-0
• Molecular Weight: 394.206
• Mol File: 133095-94-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-4-Hydroxy-4-(3-iodo-5-methoxy-4-propoxy-phenyl)-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Hydroxy-4-(3-iodo-5-methoxy-4-propoxy-phenyl)-butyric acid(133095-94-0)
• EPA Substance Registry System: (S)-4-Hydroxy-4-(3-iodo-5-methoxy-4-propoxy-phenyl)-butyric acid(133095-94-0)

Safety Data

• Hazardous Substances Data: 133095-94-0(Hazardous Substances Data)

Upstream product

• 106331-89-9 3-methoxy-4-n-propyloxy-5-iodobenzaldehyde 
• 5438-36-8 5-iodovaniline 
• 133095-93-9 (S)-4-Hydroxy-4-(3-iodo-5-methoxy-4-propoxy-phenyl)-butyric acid tert-butyl ester 

Downstream Products

• 121702-60-1 L 662418 
• 116781-15-8 (-)-L 659989 
• 133095-90-6 (S)-2-Bromo-5-(3-methanesulfonyl-5-methoxy-4-propoxy-phenyl)-tetrahydro-furan 
• 133095-99-5 (2S,5S)-2-(3-Methanesulfonyl-5-methoxy-4-propoxy-phenyl)-5-(2,3,4-trimethoxy-phenyl)-tetrahydro-furan 
• 133117-06-3 (S)-5-(3-Methanesulfonyl-5-methoxy-4-propoxy-phenyl)-dihydro-furan-2-one 
• 133095-97-3 (S)-5-(3-Methanesulfonyl-5-methoxy-4-propoxy-phenyl)-tetrahydro-furan-2-ol 
• 133095-96-2 (S)-5-(3-Methoxy-5-methylsulfanyl-4-propoxy-phenyl)-dihydro-furan-2-one 
• 140705-14-2 (2S,5S)-2-(3',4',5'-trimethoxyphenyl)-5-[3-methoxy-5-(2'-t-butyldimethylsilyloxyethanesulfonyl)-4-propoxyphenyl]tetrahydrofuran 
• 141869-80-9 (S)-5-{3-[2-(tert-Butyl-dimethyl-silanyloxy)-ethanesulfonyl]-5-methoxy-4-propoxy-phenyl}-dihydro-furan-2-one 
• 140705-19-7 (S)-5-[3-(2-Hydroxy-ethanesulfonyl)-5-methoxy-4-propoxy-phenyl]-dihydro-furan-2-one 
• 140705-18-6 (S)-5-[3-(2-Hydroxy-ethylsulfanyl)-5-methoxy-4-propoxy-phenyl]-dihydro-furan-2-one 
• 135947-75-0 MK 287 
• 133095-95-1 4[3-Methoxy-4-n-propyloxy-5-iodophenyl]-4S-butyrolactone 

Relevant articles and documents

A practical, one-pot preparation of diisopinocampheylchloroborane

A one-pot preparation of the chiral reducing agent diisopinocampheylchloroborane (Ipc2BCl) from α-pinene and borane methyl sulfide has been developed. The procedure obviates isolation of the air and moisture sensitive reagent, making it useful for large scale operations. Asymmetric reduction of ketones using the in situ prepared Ipc2BCl is comparable to that using isolated reagent.

Conversion of a silylated hemiacetal into an α-bromoether using trimethylsilylbromide. Synthesis of platelet activating factor antagonist L-659,989

An efficient synthesis of platelet activating factor antagonist L-659,989 has been achieved in ten steps from commercially available 5-iodovanillin. The key transformation converts a silylated hemi-acetal into an α-bromoether followed by a highly stereose