1331730-48-3

Basic information

• Product Name: 2-(N-(1-(4-bromophenyl)cyclopropyl)-4-(difluoromethoxy)phenylsulfonamido)acetic acid
• CAS NO: 1331730-48-3
• Molecular Weight: 476.296
• Mol File: 1331730-48-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(N-(1-(4-bromophenyl)cyclopropyl)-4-(difluoromethoxy)phenylsulfonamido)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-(1-(4-bromophenyl)cyclopropyl)-4-(difluoromethoxy)phenylsulfonamido)acetic acid(1331730-48-3)
• EPA Substance Registry System: 2-(N-(1-(4-bromophenyl)cyclopropyl)-4-(difluoromethoxy)phenylsulfonamido)acetic acid(1331730-48-3)

Safety Data

• Hazardous Substances Data: 1331730-48-3(Hazardous Substances Data)

Upstream product

• 351003-34-4 4-[(difluoromethyl)oxy]benzenesulfonyl chloride 
• 345965-54-0 1-(4-bromophenyl)-cyclopropylamine 

Downstream Products

• 1331730-44-9 2-(N-(1-(3',5'-dichlorobiphenyl-3-yl)cyclopropyl)-4-(difluoromethoxy) phenylsulfonamido)acetic acid 
• 1331730-42-7 2-(4-(difluoromethoxy)-N-(1-(2'-(trifluoromethoxy)biphenyl-4-yl)cyclopropyl)phenylsulfonamido)acetic acid 

Relevant articles and documents

Structure activity relationship studies on chemically non-reactive glycine sulfonamide inhibitors of diacylglycerol lipase

N-Benzylic-substituted glycine sulfonamides that reversibly inhibit diacylglycerol (DAG) lipases are reported. Detailed herein are the structure activity relationships, profiling characteristics and physico-chemical properties for the first reported series of DAG lipase (DAGL) inhibitors that function without covalent attachment to the enzyme. Highly potent examples are presented that represent valuable tool compounds for studying DAGL inhibition and constitute important leads for future medicinal chemistry efforts.