345965-54-0

Basic information

• Product Name: 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE
• Synonyms: 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE;1-(4-BROMOPHENYL)CYCLOPROPANAMINE;Cyclopropanamine, 1-(4-bromophenyl)-;1-(4-bromophenyl)cyclopropan-1-amine;1-(4-BROMOPHENYL)CYCLOPROPANAMINE HCL
• CAS NO: 345965-54-0
• Molecular Formula: C₉H₁₀BrN
• Molecular Weight: 212.0864
• Mol File: 345965-54-0.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 261.9 °C at 760 mmHg
• Flash Point: 112.2 °C
• Appearance: /
• Density: 1.519 g/cm³
• Vapor Pressure: 0.0112mmHg at 25°C
• Refractive Index: 1.626
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE(345965-54-0)
• EPA Substance Registry System: 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE(345965-54-0)

Safety Data

• Hazardous Substances Data: 345965-54-0(Hazardous Substances Data)

Usage

General Description

1-(4-Bromo-phenyl)-cyclopropylamine is a chemical compound with the molecular formula C9H10BrN. It is a cyclopropylamine derivative with a substituted phenyl ring containing a bromine atom. 1-(4-BROMO-PHENYL)-CYCLOPROPYLAMINE is used in organic synthesis and pharmaceutical research, where it can be utilized in the development of new drugs and biologically active compounds. Its unique structure and chemical properties make it a valuable building block for creating novel molecules with potential therapeutic applications. Additionally, it can also serve as a useful tool in studying the structure-activity relationships of various pharmacological agents.

InChI:InChI=1/C9H10BrN/c10-8-3-1-7(2-4-8)9(11)5-6-9/h1-4H,5-6,11H2

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 109-63-7 boron trifluoride diethyl etherate 
• 925-90-6 ethylmagnesium bromide 
• 557-20-0 diethylzinc 
• 345965-52-8 1-(4-bromophenyl)cyclopropanecarboxylic acid 
• 133017-10-4 Butyl 2-(4-bromophenyl)acetate 
• 360773-84-8 tert-butyl [1-(4-bromophenyl)-cyclopropyl]-carbamate 

Downstream Products

• 345965-60-8 [1-(4-Bromophenyl)-cyclopropyl]-dipropylamine 
• 952289-95-1 4-(1-(4-bromophenyl)cyclopropyl)morpholine 
• 1206594-08-2 C₁₉H₂₈BNO₃ 
• 1331730-42-7 2-(4-(difluoromethoxy)-N-(1-(2'-(trifluoromethoxy)biphenyl-4-yl)cyclopropyl)phenylsulfonamido)acetic acid 
• 1331730-44-9 2-(N-(1-(3',5'-dichlorobiphenyl-3-yl)cyclopropyl)-4-(difluoromethoxy) phenylsulfonamido)acetic acid 
• 1331730-48-3 2-(N-(1-(4-bromophenyl)cyclopropyl)-4-(difluoromethoxy)phenylsulfonamido)acetic acid 

Relevant articles and documents

METHODS FOR TREATING NEUROLOGICAL SYMPTOMS ASSOCIATED WITH LYSOSOMAL STORAGE DISEASES

Methods are provided for treating or preventing neurological symptoms and disorders which are associated with, e.g., lysosomal storage diseases. The methods include enhancing neuronal connectivity within the brain of a subject, increasing brain tissue volume, or preventing or delaying loss of brain tissue volume in a subject. Also provided are methods for monitoring the progression or regression of a neurological disorder, or assessing the onset of a neurological disorder, associated with a lysosomal storage disease, in which brain tissue volume of the subject is measured.

TREATMENT OF CILIOPATHIES USING INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE (GCS)

This disclosure relates to a method of treating a ciliopathy in a subject, the method comprising administering to the subject an effective amount of a quinuclidine compound. Also disclosed is a pharmaceutical composition comprising a quinuclidine compound for use in said method.

4,5-diphenyl isoxazole derivative as well as preparation method and application thereof

The invention discloses a 4,5-diphenyl isoxazole derivative as well as a preparation method and application thereof. Specifically, the invention relates to a 4,5-diphenyl isoxazole derivative of a structure represented by the formula (I), a stereoisomer or pharmaceutically acceptable salt of the derivative, wherein the definition of each substituent in the formula (I) is the same as that in a specification. Compounds of novel structures have the activity of inhibiting heat shock proteins HSP90, can be used for treating cancers, neurodegenerative diseases, inflammatory diseases, autoimmune diseases and ischemic brain injuries, and has wide application prospect.