1338236-30-8

Basic information

• Product Name: C₁₉H₁₈O
• CAS NO: 1338236-30-8
• Molecular Weight: 262.351
• Mol File: 1338236-30-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₈O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₈O(1338236-30-8)
• EPA Substance Registry System: C₁₉H₁₈O(1338236-30-8)

Safety Data

• Hazardous Substances Data: 1338236-30-8(Hazardous Substances Data)

Upstream product

• 54673-12-0 (2-(methoxymethoxy)ethyl)benzene 
• 6366-06-9 1-(3,5-dimethylphenyl)acetylene 
• 34818-49-0 1-methoxyisochromane 
• 60-12-8 2-phenylethanol 
• 493-05-0 isochromane 
• 103-82-2 phenylacetic acid 

Relevant articles and documents

Copper-catalyzed enantioselective additions to oxocarbenium ions: Alkynylation of isochroman acetals

We have developed an enantioselective, copper(I)-catalyzed addition of terminal alkynes to racemic isochroman acetals. This method is one of the first transition-metal-catalyzed approaches to enantioselective additions to prochiral oxocarbenium ions. In this reaction, TMSOTf is used to form the oxocarbenium ion in situ under conditions compatible with simultaneous formation of the chiral copper acetylide. By using a bis(oxazoline) ligand, good yields and enantioselectivities are observed for a variety of enantioenriched 1-alkynyl isochromans.