1338471-39-8

Basic information

• Product Name: (S)-5-(2,6-difluorophenoxy)-3-[(4-fluoro-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid
• Synonyms: (S)-5-(2,6-difluorophenoxy)-3-[(4-fluoro-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid
• CAS NO: 1338471-39-8
• Molecular Weight: 424.333
• Mol File: 1338471-39-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-5-(2,6-difluorophenoxy)-3-[(4-fluoro-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-(2,6-difluorophenoxy)-3-[(4-fluoro-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid(1338471-39-8)
• EPA Substance Registry System: (S)-5-(2,6-difluorophenoxy)-3-[(4-fluoro-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid(1338471-39-8)

Safety Data

• Hazardous Substances Data: 1338471-39-8(Hazardous Substances Data)

Upstream product

• 371-40-4 4-fluoroaniline 
• 69065-91-4 ethyl 2-(4-fluorophenylamino)-2-oxoacetate 
• 69066-43-9 2-((4-fluorophenyl)amino)-2-oxoacetic acid 

Relevant articles and documents

Synthesis and biological evaluation of novel oxalamido derivatives as caspase-3 inhibitors

A new series of 5-fluoro-3-[(4-substituted-phenylaminooxalyl)-amino]-4-oxo- pentanoic acid, 7a-c, 3-[(4-substitutedphenylaminooxalyl)- amino]-4-oxo-5-(2,3, 5,6-tetrafluoro-phenoxy)-pentanoic acid, 7d-h and 5-(2,6-difluoro-phenoxy)-3- [(substituted-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid, 7i-p have been synthesized from N-(substituted-phenyl)- oxalamic acid, 1 and their activities have been evaluated in vitro. Compounds 7b,c and k show low micromolar inhibitory activity against caspase-3.