1339022-10-4

Basic information

• Product Name: tert-butyl (2S)-2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate
• Synonyms: tert-butyl (2S)-2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate;(S)-tert-Butyl 2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate;(2S)-1-Boc-2-methylpyrrolidine-2-methanol
• CAS NO: 1339022-10-4
• Molecular Formula: C₁₁H₂₁NO₃
• Molecular Weight: 215.29
• Mol File: 1339022-10-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 293.8±13.0 °C(Predicted)
• Appearance: /
• Density: 1.055±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.77±0.10(Predicted)
• CAS DataBase Reference: tert-butyl (2S)-2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (2S)-2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate(1339022-10-4)
• EPA Substance Registry System: tert-butyl (2S)-2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate(1339022-10-4)

Safety Data

• Hazardous Substances Data: 1339022-10-4(Hazardous Substances Data)

Usage

General Description

Tert-butyl (2S)-2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate is a chemical compound with the molecular formula C11H21NO3. It is a derivative of pyrrolidine, a five-membered ring compound often found in pharmaceuticals and natural products. This specific compound contains a tert-butyl group, a hydroxymethyl group, and a methyl group attached to the pyrrolidine ring, as well as a carboxylate group. It is commonly used in the synthesis of various pharmaceuticals and may have potential applications in medicinal chemistry and drug development. Additionally, it may have biological activity and could be used as a building block for the synthesis of other compounds.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 42856-71-3 (S)-2-methylpyrrolidine-2-carboxylic acid 
• 109837-32-3 methyl (S)-2-methylpyrrolidine-2-carboxylate 
• 220060-17-3 (S)-1-tert-butyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate 
• 103336-06-7 N-(tert-butoxycarbonyl)-2-methyl-L-proline 

Downstream Products

• 1339022-13-7 potassium (S)-7a-methyl-1-oxo-5,6,7,7a-tetrahydro-1H-pyrrolizine-3-carboxylate 
• 851028-60-9 (S)-tert-butyl 2-formyl-2-methylpyrrolidine-1-carboxylate 
• 1339338-97-4 C₉H₁₁NO₃ 
• 1339021-78-1 (S)-benzyl (7a-methyl-1-oxo-5,6,7,7a-tetrahydro-1H-pyrrolizin-3-yl)carbamate 
• 1339021-94-1 (S)-3-amino-7a-methyl-5,6,7,7a-tetrahydro-1H-pyrrolizin-1-one 
• 1339021-85-0 (S)-benzyl (7a-methyl-1-oxo-5,6,7,7a-tetrahydro-1H-pyrrolizin-3-yl)(3-methylbut-2-enoyl)carbamate 

Relevant articles and documents

COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS

The invention relates to a compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, compositions comprising the same and methods of preparing and using the same. The variables are described herein.

Benzimidazole-2-piperazine compound, its pharmaceutical composition and its preparation and use

The invention relates to a benzimidazole-2-piperazine derivative and a preparing method and application of the benzimidazole-2-piperazine derivative in medicine, in particular to a novel benzimidazole-2-piperazine derivative shown in the general formula (I), a preparing method of the derivative, a pharmaceutical composition containing the derivative and application of the derivative serving as a therapeutic agent, especially serving as a poly (ADP-ribose) polymerase (PARP) inhibitor. In the general formula (I), R refers to hydrogen or halogen, G refers to carbonyl or methylene, m is 1-2, n is 1-3, and Q refers to hydrogen or C1-C4 alkyl. When X is methylene and Y is NR1 or methylene, X is NR1; R1 refers to hydrogen, C1-C6 alkyl, benzyl, COR2 or SO2R2; R2 refers to the following groups which are not substituted or groups substituted by 1-3 substituent groups, including C1-C6 alkyl, C3-C8 naphthenic base, phenyl, benzyl, naphthyl and C5-C10 aromatic heterocycle base, heterocycle in the C5-C10 aromatic heterocycle base comprises 1-3 heteroatoms selected from N, O and S, and the substituent groups are selected from the following atoms or groups of C1-C6 alkyl, C1-C6 alkoxy, halogen, amidogen, nitryl, sulfydryl, hydroxyl, cyanogroup and trifluoromethyl. The general formula (I) is shown in the specification.

GAMMA SECRETASE INHIBITORS

Disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing t