134052-62-3 Usage
Description
(1R,2S,3S,5S)-3-(4-AMINO-PHENYL)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER is a complex organic compound characterized by a bicyclic octane ring fused with an azetidine ring. This chiral molecule features a carboxylic acid and a methyl ester functional group, along with an aminophenyl substituent, which may confer potential pharmaceutical or pharmacological relevance. Its specific properties, uses, and applications are not detailed, but the structural components suggest possible interactions with biological systems.
Uses
Given the lack of specific applications provided in the materials, the potential uses of (1R,2S,3S,5S)-3-(4-AMINO-PHENYL)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER can only be hypothesized based on its structural features:
Used in Pharmaceutical Industry:
(1R,2S,3S,5S)-3-(4-AMINO-PHENYL)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER could be used as a building block or intermediate in the synthesis of pharmaceuticals due to the presence of an aminophenyl group, which is common in many drug molecules. Its chiral centers may also be relevant for the development of enantiomerically pure drugs.
Used in Chemical Research:
As a complex molecule with potential stereoisomerism, it may be utilized in academic or industrial research to study the effects of stereochemistry on biological activity or to develop new synthetic methodologies.
Used in Drug Design:
(1R,2S,3S,5S)-3-(4-AMINO-PHENYL)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER's structural components, including the azetidine ring and the carboxylic acid group, could be leveraged in drug design to target specific biological receptors or enzymes, potentially leading to the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 134052-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,0,5 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 134052-62:
(8*1)+(7*3)+(6*4)+(5*0)+(4*5)+(3*2)+(2*6)+(1*2)=93
93 % 10 = 3
So 134052-62-3 is a valid CAS Registry Number.
134052-62-3Relevant articles and documents
Synthesis, ligand binding, QSAR, and CoMFA study of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters
Carroll,Gao,Rahman,Abraham,Parham,Lewin,Boja,Kuhar
, p. 2719 - 2725 (2007/10/02)
A series of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters (2) were synthesized and found to possess high affinity for the cocaine binding site in rat striatum. The p-chloro (2c) and p-iodo (2n) compounds, which were the most potent analogues prepared, were found to be 85 and 78 times more potent than (-)-cocaine. The p-bromo (2m) and p-methyl (2d) were also 56 and 60 times more potent than cocaine. QSAR and CoMFA studies were conducted to correlate binding affinity of the cocaine analogues with their structural features. Whereas the QSAR study gave relatively low correlations, the CoMFA study gave a correlation with high predictive value.
