134306-33-5Relevant articles and documents
Squaric acid derivatives prevent the removal of N-Cbz and N-Fmoc groups under catalytic hydrogenation reaction
Shinada,Hayashi,Yoshida,Ohfune
, p. 1506 - 1508 (2007/10/03)
Under the catalytic hydrogenation conditions (H2/Pd-C), squaric acid derivatives 4 and 7 were found to be effective additives for chemoselective reduction of olefins and an alkyne having an N-Cbz or N-Fmoc group where the amino group remained to be protected. Benzyl esters having an N-Cbz or N-Fmoc group we re also selectively removed to give the corresponding N-protected carboxylic acids.