1346677-00-6

Basic information

• Product Name: (2-bromo-4-fluoro-6-{6-oxo-8-thia-4,5-diazatricyclo[7.4.0.0^2,7]trideca-1⁽⁹⁾,2⁽⁷⁾,3-trien-5-yl}phenyl)methyl acetate
• Synonyms: (2-bromo-4-fluoro-6-{6-oxo-8-thia-4,5-diazatricyclo[7.4.0.0^2,7]trideca-1⁽⁹⁾,2⁽⁷⁾,3-trien-5-yl}phenyl)methyl acetate
• CAS NO: 1346677-00-6
• Molecular Weight: 451.316
• Mol File: 1346677-00-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-bromo-4-fluoro-6-{6-oxo-8-thia-4,5-diazatricyclo[7.4.0.0^2,7]trideca-1⁽⁹⁾,2⁽⁷⁾,3-trien-5-yl}phenyl)methyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-4-fluoro-6-{6-oxo-8-thia-4,5-diazatricyclo[7.4.0.0^2,7]trideca-1⁽⁹⁾,2⁽⁷⁾,3-trien-5-yl}phenyl)methyl acetate(1346677-00-6)
• EPA Substance Registry System: (2-bromo-4-fluoro-6-{6-oxo-8-thia-4,5-diazatricyclo[7.4.0.0^2,7]trideca-1⁽⁹⁾,2⁽⁷⁾,3-trien-5-yl}phenyl)methyl acetate(1346677-00-6)

Safety Data

• Hazardous Substances Data: 1346677-00-6(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 1433990-21-6 N-(tert-butyl)-3-(diazenylmethyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide 
• 849054-12-2 N-(tert-butyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide 
• 40133-07-1 4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylic acid 
• 1346674-62-1 2,6-dibromo-4-fluorobenzyl acetate 
• 1346677-01-7 8-thia-4,5-diazatricyclo[7.4.0.0^2,7]-trideca-⁽⁹⁾,2⁽⁷⁾,3-trien-6-one 
• 62720-29-0 1,3-dibromo-5-fluoro-2-iodobenzene 
• 938467-02-8 2,6-dibromo-4-fluorobenzaldehyde 
• 1346674-69-8 (2,6-dibromo-4-fluorophenyl)methanol 

Downstream Products

• 1346676-98-9 (4-fluoro-2-{6-oxo-8-thia-4,5-diazatricyclo[7.4.0.0^2,7]trideca-1⁽⁹⁾,2⁽⁷⁾,3-trien-5-yl}-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl acetate 

Relevant articles and documents

HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS WITH ELECTROPHILIC FUNCTIONALITY

Heteroaryl pyridone and aza-pyridone amide compounds with electrophilic functionality of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.