13483-03-9

Basic information

• Product Name: 4,5-dihydrothiazol-2-amine monohydrobromide
• Synonyms: 4,5-dihydrothiazol-2-amine monohydrobromide;2-Thiazoline-2-amine·hydrobrominate;2-Iminothiazolidine hydrobromide
• CAS NO: 13483-03-9
• Molecular Formula: BrH*C₃H₆N₂S
• Molecular Weight: 183.07008
• EINECS: 236-790-0
• Mol File: 13483-03-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 221.8°Cat760mmHg
• Flash Point: 87.9°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 0.105mmHg at 25°C
• CAS DataBase Reference: 4,5-dihydrothiazol-2-amine monohydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dihydrothiazol-2-amine monohydrobromide(13483-03-9)
• EPA Substance Registry System: 4,5-dihydrothiazol-2-amine monohydrobromide(13483-03-9)

Safety Data

• Hazardous Substances Data: 13483-03-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H6N2S.BrH/c4-3-5-1-2-6-3;/h1-2H2,(H2,4,5);1H

Upstream product

• 80410-54-4 S-2-bromoethylisothiourea hydrobromide 
• 17356-08-0 thiourea 
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• 2576-47-8 2-bromoethylamine hydrobromide 

Downstream Products

• 101418-75-1 2-imino-N-phenylthiazolidinecarbothioamide 
• 102862-38-4 2-Bromo-N-(4,5-dihydro-thiazol-2-yl)-2-p-tolyl-acetamide 
• 102862-37-3 2-Bromo-2-(4-chloro-phenyl)-N-(4,5-dihydro-thiazol-2-yl)-acetamide 
• 102862-36-2 2-Bromo-N-(4,5-dihydro-thiazol-2-yl)-2-phenyl-acetamide 

Relevant articles and documents

INTRAMOLECULAR CYCLIZATION OF GUANIDINOALKANETHIOLS IN AQUEOUS SOLUTION

We have demonstrated the basic possibility of cyclizing guanidinoalkanethiols of different structure to thiazolines and thiazines.The rate of reaction depends on the pH of the medium.The concentration of buffer and the addition of heavy water and α-D,L-alanine have virtually no effect on the rate of reaction.

2,3-Dihydro-imidazo[2,1-b]-thiazole derivatives and applications thereof

This invention relates to 2,3-dihydro-imidazo[2,1-b]-thiazole derivatives of the formula: STR1 in which R represents a phenyl or substituted phenyl group, R1 represents a hydrogen atom or a phenyl substituted with a halogen atom or a C1-4 alkoxy group, R2, r3, r4 and R5, which may be the same or different, represent each a hydrogen atom, a C1-4 alkyl group or a phenyl radical, R1, r2, r3, r4 and R5 not being simultaneously hydrogen when R represents a phenyl group or a phenyl group substituted with a halogen atom or a nitro group, and their pharmaceutically acceptable acid addition salts. Said compounds have an anti-inflammatory and analgesic activity.