134836-78-5

Basic information

• Product Name: C₁₆H₁₃NO
• CAS NO: 134836-78-5
• Molecular Weight: 235.285
• Mol File: 134836-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₃NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₃NO(134836-78-5)
• EPA Substance Registry System: C₁₆H₁₃NO(134836-78-5)

Safety Data

• Hazardous Substances Data: 134836-78-5(Hazardous Substances Data)

Upstream product

• 612-16-8 (2-methoxyphenyl)methanol 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

Dialkylamino cyclopentadienyl ruthenium(II) complex-catalyzed α-alkylation of arylacetonitriles with primary alcohols

Aminocyclopentadienyl ruthenium complexes, [(η5-C 5H4NMe2)Ru(PPh3)2(CH 3CN)]+BF4- and [(η5- C5H4NEt2)Ru(PPh3) 2(CH3CN)]+BF4-, are moderately active catalysts for α-alkylation of arylacetonitriles with primary alcohols; on the other hand, the analogous unsubstituted cyclopentadienyl ruthenium complex [(η5-C5H 5)Ru(PPh3)2(CH3CN)] +BF4- shows very low catalytic activity. On the basis of experimental results and theoretical calculations, rationalization for the much higher catalytic activity of the aminocyclopentadienyl complexes over that of the unsubstituted Cp complex is provided. In the catalytic systems with the former, it is possible to regenerate the active solvento complexes via protonation of the metal hydride intermediates and subsequent ligand substitution; this process is, however, very nonfacile in the catalytic system with the latter. The Royal Society of Chemistry 2010.