1350432-40-4

Basic information

• Product Name: tert-butyl 3-(3-(1-(dimethylamino)ethyl)phenoxy)propylcarbamate
• Synonyms: tert-butyl 3-(3-(1-(dimethylamino)ethyl)phenoxy)propylcarbamate
• CAS NO: 1350432-40-4
• Molecular Weight: 322.448
• Mol File: 1350432-40-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(3-(1-(dimethylamino)ethyl)phenoxy)propylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(3-(1-(dimethylamino)ethyl)phenoxy)propylcarbamate(1350432-40-4)
• EPA Substance Registry System: tert-butyl 3-(3-(1-(dimethylamino)ethyl)phenoxy)propylcarbamate(1350432-40-4)

Safety Data

• Hazardous Substances Data: 1350432-40-4(Hazardous Substances Data)

Upstream product

• 105601-04-5 (+/-)-3-<1-(Dimethylamino)ethyl>phenol 
• 116861-31-5 tert-butyl N-(3-chloropropyl)carbamate 

Downstream Products

• 903588-24-9 N-(3-(3-(1-(dimethylamino)ethyl)phenoxy)propyl)-5-(1,2-dithiolan-3-yl)pentanamide 
• 903588-33-0 3-(3-(1-(dimethylamino)ethyl)phenoxy)propan-1-amine 

Relevant articles and documents

Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease

Lipoic acid (LA) is a natural antioxidant. Its structure was previously combined with that of the acetylcholinesterase inhibitor tacrine to give lipocrine (1), a lead compound multitargeted against Alzheimer's disease (AD). Herein, we further explore LA as a privileged structure for developing multimodal compounds to investigate AD. First, we studied the effect of LA chirality by evaluating the cholinesterase profile of 1's enantiomers. Then, a new series of LA hybrids was designed and synthesized by combining racemic LA with motifs of other known anticholinesterase agents (rivastigmine and memoquin). This afforded 4, which represents a step forward in the search for balanced anticholinesterase and antioxidant capacities.