1352410-47-9

Basic information

• Product Name: benzyl oleanolate 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1 → 3)-2,4-di-O-acetyl-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside
• Synonyms: benzyl oleanolate 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1 → 3)-2,4-di-O-acetyl-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside
• CAS NO: 1352410-47-9
• Molecular Weight: 1353.61
• Mol File: 1352410-47-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl oleanolate 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1 → 3)-2,4-di-O-acetyl-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl oleanolate 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1 → 3)-2,4-di-O-acetyl-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside(1352410-47-9)
• EPA Substance Registry System: benzyl oleanolate 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1 → 3)-2,4-di-O-acetyl-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside(1352410-47-9)

Safety Data

• Hazardous Substances Data: 1352410-47-9(Hazardous Substances Data)

Upstream product

• 1352410-45-7 benzyl oleanolate 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1 → 3)-2,4-di-O-acetyl-α-L-rhamnopyranosyl-(1 → 2)-3,4-O-isopropylidene-α-L-arabinopyranoside 

Downstream Products

• 75799-18-7 oleanolic acid 3-O-3)-O-α-L-rhamnopyranosyl-(1->2)>-α-L-arabinopyranoside 

Relevant articles and documents

Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives

Twenty-six naturally occurring oleanolic acid saponins and their derivatives, 16 of which were synthesized in this study, were preliminarily evaluated against human cancer cells. From SAR studies, the presence of α-l-rhamnosyl residue at the terminal of both C-3 and C-28 position for oleanolic acid bidesmosides was important to enhance cytotoxicity, and introducing more sugar residues at C3-OH of compound 12 with C-28 carboxylic acid is a favorable modification to ameliorate the anticancer activity. Furthermore, α-l-rhamnosyl moiety linked to C2-OH of the first monosaccharide (α-l-alabinose, β-d-xylose, β-d-galactose or β-d-glucose) in C3-OH of oleanolic acid was helpful to improve the cytotoxicity. According to the predicted log P values, lipophilicity of the synthesized saponins was not an important factor for cytotoxicity.