135574-17-3

Basic information

• Product Name: (1R,2S)-2-(2,2-Dimethoxy-ethylamino)-1,2-bis-(3,4-dimethoxy-phenyl)-ethanol
• Synonyms: (1R,2S)-2-(2,2-Dimethoxy-ethylamino)-1,2-bis-(3,4-dimethoxy-phenyl)-ethanol
• CAS NO: 135574-17-3
• Molecular Weight: 421.491
• Mol File: 135574-17-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-2-(2,2-Dimethoxy-ethylamino)-1,2-bis-(3,4-dimethoxy-phenyl)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-2-(2,2-Dimethoxy-ethylamino)-1,2-bis-(3,4-dimethoxy-phenyl)-ethanol(135574-17-3)
• EPA Substance Registry System: (1R,2S)-2-(2,2-Dimethoxy-ethylamino)-1,2-bis-(3,4-dimethoxy-phenyl)-ethanol(135574-17-3)

Safety Data

• Hazardous Substances Data: 135574-17-3(Hazardous Substances Data)

Upstream product

• 135574-68-4 (4R,5R)-4,5-Bis-(3,4-dimethoxy-phenyl)-[1,3,2]dioxathiolane 2,2-dioxide 
• 22483-09-6 2,2-dimethoxyethylamine 
• 135574-16-2 (4R,5R)-4,5-Bis-(3,4-dimethoxy-phenyl)-[1,3,2]dioxathiolane 2-oxide 
• 135574-15-1 (2R*,3R*)-2,3-bis(3,4-dimethoxyphenyl)oxirane 

Downstream Products

• 135574-18-4 Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester 
• 135574-22-0 (1R,10bS)-1-(3,4-Dimethoxy-phenyl)-6-hydroxy-8,9-dimethoxy-1,5,6,10b-tetrahydro-oxazolo[4,3-a]isoquinolin-3-one 
• 135574-21-9 (1R,10bS)-1-(3,4-Dimethoxy-phenyl)-8,9-dimethoxy-1,10b-dihydro-oxazolo[4,3-a]isoquinolin-3-one 
• 135574-67-3 [(4S,5R)-4,5-Bis-(3,4-dimethoxy-phenyl)-2-oxo-oxazolidin-3-yl]-acetaldehyde 
• 104621-38-7 (E)-2-Benzoyl-1-<(3,4-dimethoxyphenyl)methylene>-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 58-74-2 Papaverine 
• 15248-39-2 6,7-dimethoxyisoquinoline 
• 135574-20-8 (4S,5R)-3-(2,2-Dimethoxy-ethyl)-4,5-bis-(3,4-dimethoxy-phenyl)-oxazolidin-2-one 
• 140696-57-7 Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2-dihydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester 

Relevant articles and documents

Short-cut in the pomeranz-fritsch synthesis of 1-benzyl-isoquinolines; short and efficient syntheses of norrecticuline derivatives and of papaverine

A new methodology for the Pomeranz-Fritsch synthesis of 1-benzyl-1,2-dihydroisoquinolines avoiding pavine or isopavine troubles, has been developed. These intermediates could be reduced to their 1,2,3,4-tetrahydro congeners or aromatized to give isoquinolines, as it was demonstrated by the synthesis of some norrecticuline derivatives 4-7 and of papaverin 8.