135586-55-9

Basic information

• Product Name: (E)-2-(4-acetoxybenzylidene)-2,3-dihydro-1H-inden-1-one
• Synonyms: (E)-2-(4-acetoxybenzylidene)-2,3-dihydro-1H-inden-1-one
• CAS NO: 135586-55-9
• Molecular Weight: 278.307
• Mol File: 135586-55-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-acetoxybenzylidene)-2,3-dihydro-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-acetoxybenzylidene)-2,3-dihydro-1H-inden-1-one(135586-55-9)
• EPA Substance Registry System: (E)-2-(4-acetoxybenzylidene)-2,3-dihydro-1H-inden-1-one(135586-55-9)

Safety Data

• Hazardous Substances Data: 135586-55-9(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 124996-01-6 (E)-2-(4-hydroxybenzylidene)-2,3-dihydro-1H-inden-1-one 
• 5706-14-9 2-[(E)-4-methoxyphenylmethylidene]-1-indanone 
• 123-11-5 4-methoxy-benzaldehyde 
• 83-33-0 inden-1-one 

Relevant articles and documents

Light-enabled, AlCl3-catalyzed regioselective intramolecular nucleophilic addition of non-nucleophilic alkyls to alkynes

Light-enabled, AlCl3-catalyzed regioselective intramolecular nucleophilic cyclization of alkynes using non-nucleophilic alkyls as the nucleophile is reported. Upon photoexcitation, o-alkylphenyl alkynyl ketones can be transferred into (E)-photoenols. Thus, a nucleophilic methylene is formed from the non-nucleophilic alkyl. An AlCl3 catalyst can stabilize the (E)-photoenol intermediate and facilitate further intramolecular nucleophilic cyclization. DFT calculations indicated that the AlCl3-catalyzed cyclization is the regioselectivity determining step.